Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM
Biomedicines, 2021 Anorectal malformations (ARMs) are relatively common congenital abnormalities, but their pathogenesis is poorly understood. Previous gene knockout studies indicated that the signalling pathway mediated by the retinoic acid receptors (RAR) is instrumental
Manuel Mark +6 more
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Evaluation of defecative function 5 years or longer after laparoscopic-assisted pull-through for imperforate anus [PDF]
, 2011 Background: Laparoscopic anorectoplasty was introduced in 2000, but the procedure has not yet gained universal acceptance. Previous studies, including ours, reported satisfactory early postoperative outcome as compared with posterior sagittal ...
Chan, IHY, Tam, PKH, Wong, KKY, Wu, X
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Defining the molecular pathologies in cloaca malformation: similarities between mouse and human
Disease Models & Mechanisms, 2014 Anorectal malformations are congenital anomalies that form a spectrum of disorders, from the most benign type with excellent functional prognosis, to very complex, such as cloaca malformation in females in which the rectum, vagina and urethra fail to ...
Laura A. Runck +9 more
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ChildrenIn many countries, patient organisations offer advice and the exchange of experiences to Hirschsprung’s disease patients and their families. Professional treatment by experienced health care providers and the availability of life-long multidisciplinary ...
Sabine Alexander, Annette Lemli
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Clinical and radiological postoperative evaluation of posterior sagittal anorectoplasty in patients with upper and intermediate anorectal malformations [PDF]
, 1997 The PSARP is today the most-used surgical technique for correction of high and intermediary anorectal malformations.There is much controversy in the literature about the post-operative evaluation of these cases.
Lederman, Henrique Manoel +2 more
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Genome-wide copy number variation study in anorectal malformations [PDF]
, 2013 Anorectal malformations (ARMs, congenital obstruction of the anal opening) are among the most common birth defects requiring surgical treatment (2-5/10 000 live-births) and carry significant chronic morbidity.
Baum, L +36 more
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The impact of anorectal malformations on anorectal function and social integration in adulthood: report from a national database. [PDF]
, 2013 AIM: The impact of anorectal malformation (ARM) on bowel function and social, educational and occupational end-points was investigated in adult patients entered on a national database.
C. Capito +8 more
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High-resolution anorectal manometry in children [PDF]
Clinical and Experimental PediatricsAnorectal manometry is one of the motility tests in children performed by pediatric gastroenterologist. It evaluates the motility function of anorectal tract.
Yogesh Waikar
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Is a low sacral ratio associated with primary vesicoureteral reflux in children? [PDF]
, 2013 Introduction: The association of sacral anomalies with fecal incontinence and lower urinary tract dysfunction is known. The sacral ratio is proposed as a tool for evaluation of sacral development. The aim of this cross-sectional study was to evaluate the
Esfahani, S.T. +2 more
core
Gastrointestinal Manifestations in Rubinstein‐Taybi Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Rubinstein–Taybi syndrome is a rare genetic condition associated with a wide range of physical, cognitive, and developmental impairments, yet its gastrointestinal manifestations remain poorly characterized. Case reports and small series suggest a high prevalence of gastroesophageal reflux, constipation, dysphagia, and nutritional compromise ...
Mohamad Abi Nassif +3 more
wiley +1 more source