Results 31 to 40 of about 195,646 (297)

Anorexia Nervosa

, 2021
Anorexia nervosa is a common eating disorder affecting several functions of the body. Although our knowledge of the underlying mechanism has increased, therapeutic options are still limited.

core   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Early-onset anorexia nervosa: a scoping review and management guidelines

Journal of Eating Disorders
Background Anorexia nervosa (AN) is a serious multifactorial eating disorder characterized by insufficient nutritional intake to maintain a minimum normal weight for one's age and height, a fear of gaining weight and a distorted body image.
Anaël Ayrolles, Julia Clarke, Nathalie Godart, Céline André-Carletti, Clémentine Barbe, Anne Bargiacchi, Corinne Blanchet, Florence Bergametti, Valérie Bertrand, Emmanuelle Caldagues, Marylene Caquard, Danielle Castellotti, Richard Delorme, Laurence Dreno, Dominique Feneon Landou, Priscille Gerardin, Selim Guessoum, Ludovic Gicquel, Juliane Léger, Stéphanie Legras, Lucile Noel, Anne Fjellestad-Paulsen, Hélène Poncet-Kalifa, Flora Bat-Pitault, Coline Stordeur   +24 more
doaj   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

Advanced Science, EarlyView.
Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo, Yundi Wu, Shuai Zhang, Huanran Qu, Shiyang Shao, Jianqiang Chen, Xilong Wu   +6 more
wiley   +1 more source

Eficacia de los programas preventivos de trastornos alimentarios en adolescentes: análisis bibliográfico

Revista de Estudios e Investigación en Psicología y Educación, 2015
La Organización Mundial de la Salud y la unión Europea en sus estrategias de actuación en materia de salud mental, han incluido la promoción de la salud mental y la prevención de los trastornos mentales como objetivos prioritarios.
Belén Prieto-Castaño, Juan Carlos Fernández-Méndez, Rosa Marianela Salamea-Nieto, Mª Ángeles González-Fernández   +3 more
doaj   +1 more source

Mentalizing Subtypes in Eating Disorders: A Latent Profile Analysis

Frontiers in Psychology, 2020
Background: Mentalizing, the mental capacity to understand oneself and others in terms of mental states, has been found to be reduced in several mental disorders.
Giulia Gagliardini, Salvatore Gullo, Valeria Tinozzi, Monica Baiano, Matteo Balestrieri, Patrizia Todisco, Tiziana Schirone, Antonello Colli   +7 more
doaj   +1 more source

One‐Year Changes in Frailty Components After Curative Minimally Invasive Surgery for Colorectal Cancer in Older Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Frailty predicts outcomes after colorectal cancer surgery, but postoperative changes remain unclear. We previously reported improvement in FRAIL Scale‐based frail/pre‐frail status 1 year after curative minimally invasive surgery (MIS).
Hajime Ushigome, Takuya Suzuki, Shunsuke Hayakawa, Akira Kato, Yushi Yamakawa, Kenta Saito, Hiroyuki Sagawa, Ryo Ogawa, Hiroki Takahashi, Shuji Takiguchi   +9 more
wiley   +1 more source