Results 41 to 50 of about 336,604 (309)

Recent advances in understanding anorexia nervosa. [PDF]

open access: yes, 2019
Anorexia nervosa is a complex psychiatric illness associated with food restriction and high mortality. Recent brain research in adolescents and adults with anorexia nervosa has used larger sample sizes compared with earlier studies and tasks that test ...
DeGuzman, Marisa C   +2 more
core  

Eating disorder literacy and stigmatising attitudes towards anorexia, bulimia and binge eating disorder among adolescents [PDF]

open access: yes, 2016
Little research has investigated adolescents’ understanding of eating disorders (EDs) or attitudes towards people affected by EDs. This impedes the development of targeted health promotion interventions.
McNamara, N   +3 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Psilocybin increases optimistic engagement over time: computational modelling of behaviour in rats

open access: yesTranslational Psychiatry
Psilocybin has shown promise as a novel pharmacological intervention for treatment of depression, where post-acute effects of psilocybin treatment have been associated with increased positive mood and decreased pessimism.
Elizabeth L. Fisher   +6 more
doaj   +1 more source

A central role for C1q/TNF-related protein 13 (CTRP13) in modulating food intake and body weight. [PDF]

open access: yes, 2013
C1q/TNF-related protein 13 (CTRP13), a hormone secreted by adipose tissue (adipokines), helps regulate glucose metabolism in peripheral tissues. We previously reported that CTRP13 expression is increased in obese and hyperphagic leptin-deficient mice ...
Byerly, Mardi S   +5 more
core   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Social media and eating disorder psychopathology: A systematic review

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2023
The relationship between socialization through social media (SM) and eating disorders (EDs) is a serious problem for public health, largely affecting the mental health of younger people.
Paula Frieiro Padín   +3 more
doaj   +1 more source

The hysterical anorexia epidemic in the French nineteenth-century [PDF]

open access: yes, 2016
The official birth of hysterical anorexia is attributed to the French alienist Ernest Charles Lasègue (1816-1883). Starting from his 1873 article, anorexia as a ‘new’ psychopathological picture is subjected to extensive clinical and theoreticalstudy ...
Valente, Sara
core  

Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]

open access: yes, 2014
Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar   +8 more
core   +2 more sources

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe   +9 more
wiley   +1 more source

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