Results 51 to 60 of about 9,555,589 (295)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Global Poincaré inequality on Graphs via a Conical Curvature-Dimension Condition

Analysis and Geometry in Metric Spaces, 2018
We introduce and study the conical curvature-dimension condition, CCD(K, N), for finite graphs.We show that CCD(K, N) provides necessary and sufficient conditions for the underlying graph to satisfy a sharp global Poincaré inequality which in turn ...
Lakzian Sajjad, Mcguirk Zachary
doaj   +1 more source

Aligned SICs and embedded tight frames in even dimensions

, 2019
Alignment is a geometric relation between pairs of Weyl-Heisenberg SICs, one in dimension $d$ and another in dimension $d(d-2)$, manifesting a well-founded conjecture about a number-theoretical connection between the SICs. In this paper, we prove that if
Andersson, Ole, Dumitru, Irina
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Another dimension to calcium signaling: a look at extracellular calcium

Journal of Cell Science, 2005
Cell biologists know the calcium ion best as a vital intracellular second messenger that governs countless cellular functions. However, the recent identification of cell-surface detectors for extracellular Ca2+ has prompted consideration of whether Ca2 ...
A. Hofer
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Another essential dimension of priorities: Spatial heterogeneity and temporal stability of climate refugia

Global Ecology and Conservation
Prioritization analysis with climate dynamics has become a critical, complex, and popular topic for conservation planning, providing opportunities for achieving co-benefits of climate stabilization, biodiversity conservation, and other goals.
Zhibo Du, Longqin Li, Jingya Zhang, Zilin Shi, Xiaoqin Chen, Binyue Kang, Weiqing Meng, Hongyuan Li   +7 more
doaj   +1 more source

GENERALIZATION TECHNIQUE FOR 2D+SCALE DHE DATA MODEL [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Different users or applications need different scale model especially in computer application such as game visualization and GIS modelling. Some issues has been raised on fulfilling GIS requirement of retaining the details while minimizing the redundancy
H. Karim, A. A. Rahman, P. Boguslawski
doaj   +1 more source

Trisecant Lemma for Non Equidimensional Varieties

, 2007
The classic trisecant lemma states that if $X$ is an integral curve of $\PP^3$ then the variety of trisecants has dimension one, unless the curve is planar and has degree at least 3, in which case the variety of trisecants has dimension 2. In this paper,
Alexei Kanel-Belov, B. Adlandsvik, B. Adlandsvik, Jeremy Yirmeyahu Kaminski, M. Barnabei, Mina Teicher, Z. Ran   +6 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source