Results 31 to 40 of about 3,271,002 (290)

Strongly Hierarchical Factorization Machines and ANOVA Kernel Regression

, 2018
High-order parametric models that include terms for feature interactions are applied to various data mining tasks, where ground truth depends on interactions of features.
Alvari, Hamidreza, Guo, Ruocheng, Shakarian, Paulo   +2 more
core   +1 more source

Efficient ANOVA for directional data [PDF]

, 2017
In this paper, we tackle the ANOVA problem for directional data. We apply the invariance principle to construct locally and asymptotically most stringent rank-based tests.
Ley, Christophe, Swan, Yvik, Verdebout, Thomas   +2 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Pre-exposure prophylaxis persistence at two sites in an integrated primary health care programme in South Africa

Frontiers in Public Health
IntroductionHIV continues to be a public health concern and pre-exposure prophylaxis (PrEP) has become an important HIV prevention strategy. We examined PrEP persistence over time in two health facilities in Gauteng, South Africa.MethodsWe conducted a ...
Nosipho Shangase, Anele Jiyane, Fezile Buthelezi, Cara O’Connor, Ben Brown, Kate Rees, Kate Rees   +6 more
doaj   +1 more source

Transition to an in-facility electronic Tuberculosis register: Lessons from a South African pilot project

Southern African Journal of HIV Medicine, 2020
Background: South Africa has one of the highest incidences of Tuberculosis (TB) globally. High co-morbid HIV prevalence complicates TB management and treatment outcomes.
Hanlie Myburgh, Remco P.H. Peters, Theunis Hurter, Cornelius J. Grobbelaar, Graeme Hoddinott   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Upaya PT. Perkebunan Nusantara VIII Dalam Mengembangkan Ekspor Teh Hitam Ke Malaysia [PDF]

, 2017
Indonesian is fifth tea exportir country in the world from volume side after Srilanka, Kenya, Tiongkok and India. Compared than kind of other teas, the black tea is the most produced tea namely about 78%, followed green tea 20% and the rest is oolong tea
Anova, A. (Alvianti), Pazli, P. (Pazli)
core  

ERP evidence suggests executive dysfunction in ecstasy polydrug users [PDF]

, 2013
Background: Deficits in executive functions such as access to semantic/long-term memory have been shown in ecstasy users in previous research. Equally, there have been many reports of equivocal findings in this area.
A Gamma, A Miyake, A Pazos, AC Parrott, AG Verstraete, AJ Saykin, AP Burgess, B Kopp, C Casco, C Montgomery, C Montgomery, C Montgomery, C Montgomery, C Montgomery, C Whitney, C. A. Roberts, C. Montgomery, D Badre, D Davison, DE Hinkle, DM McDowell, DT Stuss, E Jefferies, EM Bekker, F. Tames, G Jager, G Kanayama, HC Fox, J Cole, J. E. Fisk, JA Horne, JE Fisk, JH Halpern, JR Folstein, M Terman, MA Wetherell, MJ Morgan, N Yeung, PN Murphy, RL Carhart-Harris, RM Ruff, RM Shiffrin, S Bhattachary, S Mejias, S Nieuwenhuis, S Rossi, S Sola de, S Suwazono, S. H. Fairclough, SJ Luck, SL Rosell, T Akerstedt, V Veen van, W Ritter   +53 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source