Results 111 to 120 of about 138,806 (296)
Med Research, EarlyView.White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
Prioritizing objectives to evaluate the environmental, economic and social impacts of biofuel in Spain [PDF]
A variety of opinions either in favour or against development of biofuels has risen in the last years related to the environmental, economic and social impacts that its diffusion could entail compared to petroleum. Although the EU, in general, and Spain,
Fernadez-Tirado, Francisca +1 more
core +1 more source
Congestion, decongestion, renal function and diuretics in (ESC) heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus +2 more
wiley +1 more source
Phytotherapy Research, EarlyView.Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu +10 more
wiley +1 more source
Features of various cardiac markers in the diagnosis of acute coronary syndrome (review)
Атеросклероз, 2014 Currently, the incidence of coronary heart disease (CHD) in the countries of the European Region and North America, one million of the population accounts for 30–40 thousand of patients, and the mortality rate of 700.000 cases per year.
N. N. Yarohno +2 more
doaj
Lyapunov exponents of cocycles over non-uniformly hyperbolic systems
, 2017 We consider linear cocycles over non-uniformly hyperbolic dynamical systems. The base system is a diffeomorphism $f$ of a compact manifold $X$ preserving a hyperbolic ergodic probability measure $\mu$.
Kalinin, Boris, Sadovskaya, Victoria
core +1 more source
Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A
Phytotherapy Research, EarlyView.ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen +16 more
wiley +1 more source
Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function
Phytotherapy Research, EarlyView.Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng +8 more
wiley +1 more source
Designing effective contracts within the buyer-seller context: a DEMATEL and ANP study [PDF]
, 2013 This study examines the factors that contribute to effective contract design within the context of buyer-seller relationship. Research streams on contract factors, supply chain factors, environmental factors, and competitive factors were reviewed to ...
Vlachos, Ilias
core
Sustainable Development, EarlyView.ABSTRACT Sustainable development transforms production systems, requiring integrated environmental, social, and economic strategies. Energy systems are key agro‐industrial supply chains in developing countries. Brazil's soybean supply chain impacts Gross Domestic Product, mainly through exports.
Aline Veronese da Silva +3 more
wiley +1 more source