Results 121 to 130 of about 1,362,424 (329)

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

open access: yesAdvanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang   +17 more
wiley   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

open access: yesAdvanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

open access: yesAdvanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang   +3 more
wiley   +1 more source

Internet of Things‐Based Framework Application at a University Campus Scale: Linking Smart Monitoring Systems and Stormwater Management

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study presents an Internet of Things‐based stormwater monitoring framework piloted at the University of Maryland campus to support Municipal Separate Stormwater Sewer System compliance and adaptive planning. Developed with key campus stakeholders, the framework integrates real‐time sensor deployment, data‐informed insights on runoff and water ...
Qianyao Si   +16 more
wiley   +1 more source

Accurate and Anti‐Interference Control of Computer Vision‐Assisted Light‐Driven Liquid Crystal Elastomer Actuator

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This article introduces a computer vision‐assisted control strategy for light‐driven liquid crystal elastomer actuators. Through negative feedback regulation, the liquid crystal elastomer actuator exhibits accurate and stable bending deformation in complex environments.
Wei Zhang   +6 more
wiley   +1 more source

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