Results 31 to 40 of about 1,295,796 (230)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The basic geometry of Witt vectors, I: The affine case [PDF]
, 2015 We give a concrete description of the category of etale algebras over the ring of Witt vectors of a given finite length with entries in an arbitrary ring.
Borger, James
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Height bounds and the Siegel property [PDF]
, 2018 Let $G$ be a reductive group defined over $\mathbb{Q}$ and let $\mathfrak{S}$ be a Siegel set in $G(\mathbb{R})$. The Siegel property tells us that there are only finitely many $\gamma \in G(\mathbb{Q})$ of bounded determinant and denominator for which ...
Orr, Martin
core +2 more sources
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
InsectsThe red imported fire ant (RIFA, Solenopsis invicta Buren) represents a significant invasive pest in China, exerting extensive negative impacts on ecosystems.
Yunbo Song +7 more
doaj +1 more source
Heliyon, 2019 In this work, a set of analytical expressions to tailor the numerical aperture of cone-shaped step optical fibers is proposed. The expressions are derived from the geometrical study of light-ray tracing at the cone-shaped tip of a regular step-index ...
Brayan Patiño-Jurado +2 more
doaj +1 more source
Mammalogy Notes, 2020 A pesar de su amplia distribución geográfica, los patrones de abundancia del tigrillo (Leopardus pardalis) son poco conocidos en paisajes transformados.
Orlando Padilla-Rivera +2 more
doaj +1 more source
Characteristic cycles and Gevrey series solutions of $A$-hypergeometric systems [PDF]
, 2019 We compute the $L$-characteristic cycle of an $A$-hypergeometric system and higher Euler-Koszul homology modules of the toric ring. We also prove upper semicontinuity results about the multiplicities in these cycles and apply our results to analyze the ...
Berkesch, Christine +1 more
core +2 more sources
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source