Results 71 to 80 of about 122,865 (268)
ANT4KIDS: ART, NEUROSCIENCE AND TECHNOLOGY FOR KIDS
IBRO Neuroscience Reports, 2023 María Castelló +7 more
doaj +1 more source
Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling
Advanced Science, EarlyView.Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha +13 more
wiley +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
Recent advances of privacy-preserving machine learning based on (Fully) Homomorphic Encryption
Security and SafetyFully Homomorphic Encryption (FHE), known for its ability to process encrypted data without decryption, is a promising technique for solving privacy concerns in the machine learning era. However, there are many kinds of available FHE schemes and way more
Hong Cheng
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo +9 more
wiley +1 more source
THE MUSEUM AS INSTITUTIONAL ACTOR: STRATEGIC COMMUNICATION AND NARRATIVE IDENTITY IN THE MEDICAL UNIVERSITY [PDF]
Social Sciences and Education Research ReviewThis article proposes an analysis of the role played by the university museum in constructing and communicating institutional identity, starting from the concept of the “museum-actor” – an entity that does not confine itself to preserving heritage, but ...
Xenia Negrea
doaj +1 more source
Evolution of Physical Intelligence Across Scales
Advanced Intelligent Discovery, EarlyView.By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu +7 more
wiley +1 more source
Acta Haematologica Oncologica TurcicaAim: This study aimed to assess the real-world performance of elranatamab in terms of its effectiveness, safety, and tolerability among patients diagnosed with triple-class refractory-multiple myeloma (TCR-MM) who have undergone extensive prior treatment.
Ant Uzay
doaj +1 more source
The dual strategy: resisting and tolerating pathogens in ant colonies [PDF]
Royal Society Open ScienceAnt colonies are vulnerable to disease outbreaks due to their dense, genetically related populations and confined living conditions. To mitigate the impact of entomopathogens such as Beauveria bassiana, ants employ resistance strategies to reduce ...
Quentin Avanzi, Claire Detrain
doaj +1 more source