Results 101 to 110 of about 1,817,602 (304)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Local and regional drivers of ant communities in forest-grassland ecotones in South Brazil: A taxonomic and phylogenetic approach.

PLoS ONE, 2019
Understanding biological community distribution patterns and their drivers across different scales is one of the major goals of community ecology in a rapidly changing world.
William Dröse, Luciana Regina Podgaiski, Camila Fagundes Dias, Milton de Souza Mendonça   +3 more
doaj   +1 more source

Small-scale drivers on plant and ant diversity in a grassland habitat through a multifaceted approach. [PDF]

PeerJ, 2021
Mugnai M, Frasconi Wendt C, Balzani P, Ferretti G, Dal Cin M, Masoni A, Frizzi F, Santini G, Viciani D, Foggi B, Lazzaro L.   +10 more
europepmc   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Mirmecofauna asociada con sistemas agroforestales en el Corredor Biológico Mesoamericano en Tabasco, México Mirmecofauna associated with agroforestry systems in the Mesoamerican Biological Corridor in Tabasco, Mexico

Revista Mexicana de Biodiversidad, 2013
Se evaluaron la riqueza, la abundancia y la distribución de hormigas como indicadores para monitoreo ecológico en los sistemas agroforestales en 3 regiones dentro del Corredor Biológico Mesoamericano en Tabasco, México.
Noel A. González-Valdivia, Gabriela González-Escolástico, Everardo Barba, Salvador Hernández-Daumás, Susana Ochoa-Gaona   +4 more
doaj  

Ant Diversity and Community Composition in Alpine Tree Line Ecotones. [PDF]

Insects, 2021
Guariento E, Fiedler K.
europepmc   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Taxonomic and functional ecology of montane ants

Frontiers of Biogeography, 2017
Why is biological diversity distributed in the way that it is? This question has been central to ecology and biogeography for centuries and is of great importance for pure and applied reasons.
Tom Rhys Bishop
doaj   +1 more source

Evolution of Physical Intelligence Across Scales

Advanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu, Tianyun Huang, Aming Li, Pengyu Lv, Tingting Qin, Wenhui Chen, Hui Wei, Huiling Duan   +7 more
wiley   +1 more source