Antacid Use and De Novo Brain Metastases in Patients with Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer Who Were Treated Using First-Line First-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. [PDF]
PLoS ONE, 2016 Antacid treatments decrease the serum concentrations of first-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs), although it is unknown whether antacids affect clinical outcomes. As cerebrospinal fluid concentrations of
Yu-Mu Chen +14 more
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New Natural Marine Antacid Drug from Cuttlebone [PDF]
Pharmaceutical Sciences, 2018 Background: Antacids are the most commonly used medications for fast symptomatic relief of gastric disorders. Because of adverse effects, low efficiency and the high cost of some chemical antacids, identifying a natural medicine with high efficiency and ...
Azar Mostoufi +3 more
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Gastroesophageal reflux and antacid therapy in IPF: analysis from the Australia IPF Registry
BMC Pulmonary Medicine, 2019 Background and objective Gastroesophageal reflux disease (GORD) is highly prevalent in idiopathic pulmonary fibrosis (IPF) and may play a role in its pathogenesis.
Helen E. Jo +16 more
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In Vitro Evaluation of Drug–Drug Interaction Between Gliclazide and Antacids at the Absorption Level [PDF]
PharmaceuticalsBackground: The antidiabetic drug gliclazide is often taken with antacids due to its gastrointestinal side effects. However, patients rarely report antacid use, making drug–drug interactions a potential cause of therapy failure.
Slavica Lazarević +6 more
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Effect of antacid gastric syrups on surface properties of dental restorative materials: an in vitro analysis of roughness and microhardness [PDF]
BMC Oral HealthSummary Objectives The aim of this in-vitro study was to evaluate the effects of antacid gastric syrups on the surface roughness and microhardness of restorative dental materials.
Fikri Öcal, Burak Dayi
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Exploratory analyses of meal‐induced heartburn identify distinct clinical phenotypes of gastroesophageal reflux disease [PDF]
Physiological ReportsSymptoms in symptomatic GERD patients result from esophageal acid exposure and are treated with agents that inhibit gastric acid secretion. We analyzed data from a clinical trial evaluating the effect of ranitidine plus antacid on heartburn severity in ...
Jerry D. Gardner +1 more
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Establishment of the mechanism of purification and levigation of green chemistry-assisted biocomposites of red ochre (Gairika): synthesis, characterization, and antibacterial, prebiotic, antioxidant, and antacid activities of the traditional Ayurvedic medicine Laghu Sutashekhara Rasa [PDF]
Frontiers in Chemistry, 2023 Gairika (red ochre) has a long history of influencing human civilization. Gairika is a rich source of nutrients used for reproductive and brain health.
Vaibhav Charde +16 more
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Antipeptic activity of antacids [PDF]
Gut, 1971 An in vitro experiment based on the digestion of haemoglobin with pepsin was carried out to test the claim made by some manufacturers that the antacids used in their proprietary preparations had an intrinsic antipeptic activity independent of the change brought about by alteration of pH. In no case could these claims be substantiated.
J. T. Kuruvilla
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Association between Antacid Exposure and Risk of Interstitial Lung Diseases [PDF]
Tuberculosis and Respiratory DiseasesBackground The mechanisms leading to lung fibrosis are still under investigation. This study aimed to demonstrate whether antacids could prevent the development of interstitial lung disease (ILD).
Soohyun Bae +5 more
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Treatment of Heartburn: A Survey of Ontario and Québec Community Pharmacists [PDF]
PharmacyThe shift of proton pump inhibitors (PPIs) from prescription to nonprescription (nonRx) status in Canada has altered pharmacist treatment options for heartburn.
Nardine R. Nakhla +2 more
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