Results 1 to 10 of about 7,066 (154)

The effect of antacid and mineral supplements on bictegravir pharmacokinetics: results from a Phase 1, open-label, drug–drug interaction study [PDF]

Antimicrobial Agents and Chemotherapy
The mechanism of action of integrase strand transfer inhibitors involves binding to magnesium ions in the active site of the HIV integrase enzyme, making them susceptible to chelation-type drug–drug interactions with metal cation–containing medications ...
Priyanka Arora, Jason T. Hindman, Steve West, John Ling, Ramesh Palaparthy, Dhananjay D. Marathe   +5 more
doaj   +2 more sources

Effect of an alginate-based antacid and simulated gastric acid on the surface roughness and color stability of CAD/CAM resin-based materials [PDF]

BMC Oral Health
Background This in vitro study aimed to evaluate the effect of simulated gastric fluid (SGF) and an alginate-based antacid on the surface roughness and color stability of two additively manufactured (AM) and one subtractively manufactured (SM) resin ...
Didar Dilan Hartavi, Neşe Cızıroğlu, Rafat Sasany, Muammer Alhan Babat, Seyed Ali Mosaddad   +4 more
doaj   +2 more sources

Exploratory analyses of meal‐induced heartburn identify distinct clinical phenotypes of gastroesophageal reflux disease [PDF]

Physiological Reports
Symptoms in symptomatic GERD patients result from esophageal acid exposure and are treated with agents that inhibit gastric acid secretion. We analyzed data from a clinical trial evaluating the effect of ranitidine plus antacid on heartburn severity in ...
Jerry D. Gardner, George Triadafilopoulos   +1 more
doaj   +2 more sources

Prevalence and characterization of bacterial rectal colonization patterns in pediatric patients: A cross-sectional study [PDF]

New Microbes and New Infections
Background: Antimicrobial resistance is a major public health concern requiring ongoing surveillance to determine its extent and associated factors. This study evaluates bacterial isolates from pediatric patients in terms of distribution, resistance ...
Aynaa Al-Khatib, Amal Naous, Elie Salem Sokhn   +2 more
doaj   +2 more sources

Effect of antacid gastric syrups on surface properties of dental restorative materials: an in vitro analysis of roughness and microhardness [PDF]

BMC Oral Health
Summary Objectives The aim of this in-vitro study was to evaluate the effects of antacid gastric syrups on the surface roughness and microhardness of restorative dental materials.
Fikri Öcal, Burak Dayi
doaj   +2 more sources

Comparison of Acid-neutralizing capacity of antacids in Erbil City

Zanco Journal of Medical Sciences, 2021
Background and objective: Antacids are basic substances that can neutralize hydrochloric acid and reduce gastric acidity. They are over the counter drugs used to treat dyspepsia. The most commonly used antacids are sodium bicarbonate, magnesium hydroxide,
Dina Aziz Boya, Jwan Mohammed Ahmed
doaj   +1 more source

Antacid Use and De Novo Brain Metastases in Patients with Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer Who Were Treated Using First-Line First-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. [PDF]

PLoS ONE, 2016
Antacid treatments decrease the serum concentrations of first-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs), although it is unknown whether antacids affect clinical outcomes. As cerebrospinal fluid concentrations of
Yu-Mu Chen, Chien-Hao Lai, Huang-Chih Chang, Tung-Ying Chao, Chia-Cheng Tseng, Wen-Feng Fang, Chin-Chou Wang, Yu-Hsiu Chung, Yi-Hsi Wang, Mao-Chang Su, Shih-Feng Liu, Kuo-Tung Huang, Hung-Chen Chen, Ya-Chun Chang, Meng-Chih Lin   +14 more
doaj   +1 more source

Nanoantidote for repression of acidosis pH promoting COVID‐19 infection

View, 2022
Acidosis, such as respiratory acidosis and metabolic acidosis, can be induced by coronavirus disease 2019 (COVID‐19) infection and is associated with increased mortality in critically ill COVID‐19 patients.
Qidong Liu, Huitong Ruan, Zhihao Sheng, Xiaoru Sun, Siguang Li, Wenguo Cui, Cheng Li   +6 more
doaj   +1 more source

Perspectives of Parents and Health Care Providers about (Non)Medical Treatment in Infants with Reflux

Pharmacy, 2020
Background: Reflux occurs in 50% of healthy infants at some point. This is most often a physiological condition and does not require drug treatment.
Santina Gorsen, Koen Boussery, Myriam Van Winckel, Rolinde Demeyer, Eline Tommelein   +4 more
doaj   +1 more source

Microbiological Evaluation of some Oral Antacid Suspensions Sold in Delta State, Nigeria

Journal of Applied Sciences and Environmental Management, 2021
Pharmaceutical products (non-sterile) are faced with the challenges of not exceeding the minimum limit of microbial presence tolerated for the respective formulations.
C.O. Anie, S.E. Okafo
doaj   +1 more source