Results 91 to 100 of about 31,957 (285)

Testing for Placebo Effects Using Data from Blinded, Randomized Controlled Trials [PDF]

This paper proposes a test for the existence of placebo effects, as described by the so-called expectancy theory. This theory, which is the dominant medical theory of how placebo effects operate, posits that health outcomes rise in individuals' beliefs ...
Anup Malani
core  

Obesity is positively associated with dehydroepiandrosterone sulfate concentrations at 7 y in Chilean children of normal birth weight. [PDF]

, 2013
BACKGROUND: In low-birth-weight girls, obesity increases the risk of premature adrenarche and metabolic complications. However, the consistency of this association in normal-birth-weight children and its potential mediators remain unknown.
Baquedano, Camila Corvalán, Charkaluk, Cohen, Cook, Corvalán, de Onis, D’Adamo, Fernandez, Genazzani, Gonzales, Guercio, Guercio, Havelock, Ibáñez, Ibáñez, Ibáñez, Idkowiak, Iñiguez, Jean, Kain, Kelnar, Khan, l’Allemand, Mentzel, Mericq, Ong, Palmert, Parker, Popkin, Rainey, Remer, Remer, Ricardo Uauy, Rittmaster, Rosenfield, Silfen, Slaughter, Smith, Sopher, Tanner, Topor, Utriainen, Verónica Mericq, Williams, Yu   +45 more
core   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

JPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano, Elisabetta Augustoni, Antonio Pizzol, Anna Opramolla, Cristina Chiadò, Anna Zagaria, Irene Esposito, Giulia Roberto, Alice Ponte, Andrea Evangelista, Paola Quarello, Michele Pinon, Pier Luigi Calvo   +12 more
wiley   +1 more source

An Early Holiday Surprise: Cholecystitis Wrapped in Takotsubo Cardiomyopathy [PDF]

, 2020
This is a novel case report of a 44-year-old woman who presented to the emergency department with epigastric pain wrapping around to her back. She had no risk factors for cardiac disease, but her initial electrocardiogram (ECG) showed a Wellens syndrome ...
Gould, Kevin, Miller, Stephen, Moll, Joel   +2 more
core  

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Assembled pH-Responsive Gastric Drug Delivery Systems Based on 3D-Printed Shells

Pharmaceutics
Gastric acid secretion is closely associated with the development and treatment of chronic gastritis, gastric ulcers, and reflux esophagitis. However, gastric acid secretion is affected by complex physiological and pathological factors, and real-time ...
Haoye Bei, Pingping Zhao, Lian Shen, Qingliang Yang, Yan Yang   +4 more
doaj   +1 more source

Renal Aspects of Peptic Ulcer Pharmacology

Canadian Journal of Gastroenterology, 1992
Medications to treat peptic ulcer disease are used widely and may have adverse effects on renal function. Similarly, renal dysfunction may alter the pharmacokinetics of this diverse group of medications resulting in dosage adjustments.
Daniel Muruve, Ellen Burgess
doaj   +1 more source

Gastro-oesophageal reflux: An overview of the cost-effectiveness of pharmacotherapeutic treatment options

South African Family Practice, 2016
Gastro-oesophageal reflux disease (GORD) produces symptoms that cause great irritation to the patient. Pharmacotherapeutic management is directed at minimising these symptoms and reducing the causative factors, e.g.
Gustav Schellack, J. C. Meyer, Natalie Schellack   +2 more
doaj   +1 more source

Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment [PDF]

, 2007
The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77
Antoine Tshomba, Benjamin Jeffs, Borchert M, Conrad JL, Daniel G. Bausch, Florimond Tshioko, Hilde Sleurs, Jean‐Jacques Muyembe‐Tamfum, Johnson ED, Maria D. Van Kerkhove, Martini GA, Matthias Borchert, Modeste Libande, Nikiforov VV, Pat Campbell, Patricia Pirard, Pierre E. Rollin, Robert Colebunders, Sabue Mulangu, Simon Mardel, Slenczka WG   +20 more
core   +2 more sources

Incidence and Early‐Life Risk Factors for Food Allergy in a Spanish Birth Cohort

Acta Paediatrica, EarlyView.
ABSTRACT Aim The prevalence of food allergy has increased in recent decades. We aimed to determine the cumulative incidence of food allergy in early childhood and to identify associated risk factors. Methods We conducted a prospective birth cohort study including 1006 newborns recruited over one year at a single hospital in Spain and followed until 4 ...
Jorge García‐Ezquiaga, Patricia Torija‐Berzal, Sergio Quevedo‐Teruel, Teresa Bracamonte‐Bermejo, Patricia Alonso‐López, Luis Echeverría‐Zudaire, María Luz García‐García   +6 more
wiley   +1 more source