Results 171 to 180 of about 182,741 (305)

Ketamine Dosing Across Clinical Indications: A Narrative Review Organized by Proposed NMDA-Related Mechanisms. [PDF]

J Clin Pharmacol
Glue P, Beaglehole B.
europepmc   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Comment on: Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus. [PDF]

J Antimicrob Chemother
Pinder C, Birch M, Oliver JD, Law D, Zinzi D, Rex JH.   +5 more
europepmc   +1 more source

BACTERIOLOGICAL ANTAGONISMS

American Journal of Public Health, 1923
openaire   +3 more sources

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

Kindling antagonism: an arrest of epileptogenesis?

, 2018
Concurrent alternating stimulation of two limbic sites culminates in typical kindling of generalized seizures from one site (dominant), whereas the other site (suppressed) supports only nongeneralized seizures for as long as stimulation of the ...
Kirkby, Robert Duncan
core  

Machiavellianism, level of personality functioning, and maladaptive personality traits: mediation analyses in a clinical sample. [PDF]

Front Psychiatry
Láng A, Kiss TC, Kiss BL, Láng DÁ.
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Olfactory receptor antagonism between odorants

, 2004
The detection of thousands of volatile odorants is mediated by several hundreds of different G protein-coupled olfactory receptors (ORs). The main strategy in encoding odorant identities is a combinatorial receptor code scheme in that different odorants ...
Omura, Masayo, Kataoka, Hiroshi, Oka, Yuki, Touhara, Kazushige   +3 more
core  

Discovery and Cryo-EM-Guided Development of a Neuropilin-2-Binding Aptamer for Receptor Antagonism. [PDF]

J Am Chem Soc
Jiang K, Kacherovsky N, Wang T, Wu AY, Liu GW, Cardle II, Ureel J, Pippin JW, Salipante SJ, Shankland SJ, Pun SH.   +10 more
europepmc   +1 more source