Results 51 to 60 of about 75,188 (269)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Advanced Dielectric Resonator Antenna Technology for 5G and 6G Applications

open access: yesSensors
We review dielectric resonator antenna (DRA) designs. This review examines recent advancements across several categories, specifically focusing on their applicability in array configurations for millimeter-wave (mmW) bands, particularly in the context of
Yingqi Zhang   +4 more
doaj   +1 more source

Integrated Miniature Multiband Antenna Designed for WWD and SAR Assessment for Human Exposure

open access: yesInternational Journal of Antennas and Propagation, 2021
The article introduces a new, low-cost, integrated, multiband antenna design intended for wristbands and wearable wireless devices (WWD). With a miniaturized planar square-shape sizing 29 × 29 mm2, the antenna can fit easily inside WWDs.
Brahim Fady   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Strategies of a thirteen year surveillance programme on Aedes albopictus (Stegomyia albopicta) in southern Switzerland

open access: yesParasites & Vectors, 2015
Background In Ticino, a canton located south of the Alps in Switzerland, a surveillance programme on Aedes albopictus (Stegomyia albopicta) started in 2000 seeing that the region was considered at high risk of introduction based on the rapid spread of ...
Eleonora Flacio   +4 more
doaj   +1 more source

Dual-Mode Microstrip Patch Bandpass Filters With Generalized Frequency Responses

open access: yesIEEE Access, 2019
A basic two-pole bandpass filter based on the dual-mode square patch resonator is presented and analyzed to realize generalized frequency responses in terms of two finite transmission zeros (FTZs).
Qing Liu   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Accurate DOA Estimations Using Microstrip Adaptive Arrays in the Presence of Mutual Coupling Effect

open access: yesInternational Journal of Antennas and Propagation, 2013
A new mutual coupling calibration method is proposed for adaptive antenna arrays and is employed in the DOA estimations to calibrate the received signals.
Qiulin Huang   +3 more
doaj   +1 more source

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