Results 41 to 50 of about 62,792 (336)

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Effects of inclusion of proprioception training in the recovery of adults submitted to anterior cruciate ligament reconstruction surgery: a systematic review

Revista da Educação Física, 2020
Anterior cruciate ligament (ACL) rupture is an injury in young adults, triggering undesirable neuromuscular effects. A rehabilitation program is structured with exercises that aid in intensive care training, and proprioceptive training has been proposed ...
Wdson Donizete Da Silva Costa, Flávio Ricardo Guilherme, Stevan Ricardo dos Santos, Eduardo Gauze Alexandrino, Vânia Renata Guilherme, Wilson Rinaldi   +5 more
doaj   +1 more source

Knee Flexors Maximum Effective Angle Variation after Anterior Cruciate Ligament Reconstruction with Hamstring Graft

International Journal of Physiotherapy, 2021
Background: During the anterior cruciate ligament reconstruction, the graft is taken from the distal hamstring tendon, which causes morphological and neurological changes in these muscles, particularly on the maximum effective angle of the knee flexors ...
Hugues FRUYTIER, Jean MAZEAS, Maude TRAULLÉ, Amaury VANDEBROUCK, Pascal DUFFIET, Louis RATTE, Florian FORELLI   +6 more
doaj   +1 more source

Right knee ACL, PCL and MCL reconstruction with sports-related anxiety [PDF]

Introduction: JM, a 20-year-old male professional ice hockey player, presented with a 2-week history of lack of range of motion, weakness, and pain in his right knee, after a 2-year post-medical collateral ligament repair of the right knee and 3 year ...
Najamus-Saqib Khan, Kazi, Nulkar, Avnee
core   +2 more sources

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Advanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma   +8 more
wiley   +1 more source

Effectiveness of Reconstruction of the Anterior Cruciate Ligament With Quadrupled Hamstrings and Bone-Patellar Tendon-Bone Autografts: An In Vivo Study Comparing Tibial Internal-External Rotation [PDF]

, 2007
Background: The 2 most frequently used autografts for anterior cruciate ligament reconstruction are the bone-patellar tendon- bone and the quadrupled hamstrings tendon.
Chouliaras, Vasileios, Georgoulis, Anastasios D., Moraiti, Constantina Moraiti, Ristanis, Stavros, Stergiou, Nikolaos   +4 more
core   +2 more sources

Use of Posterior Hamstring Harvest During Anterior Cruciate Ligament Reconstruction in the Pediatric and Adolescent Population. [PDF]

, 2018
Background:Posterior hamstring harvest has been described in the adult population in a limited fashion, but no study is available describing the use of posterior hamstring harvest in an active pediatric and adolescent cohort.
Janghala, Abhinav, Khanna, Krishn, Pandya, Nirav K   +2 more
core   +2 more sources

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Anterior cruciate ligament reconstruction

Journal of ISAKOS, 2016
Anterior cruciate ligament (ACL) reconstruction is a common procedure performed by orthopaedic surgeons, particularly in association with sports-related injuries. Over the past 10 years, a renewed interest in the native anatomy of the ACL has facilitated a progression from non-anatomic to more anatomic reconstruction techniques.
Sebastián Irarrázaval, Sebastián Irarrázaval, Moises Cohen, Masahiro Kurosaka, Freddie H. Fu   +4 more
openaire   +2 more sources

A Technique of Improved Medial Meniscus Visualization by Anterior Cruciate Ligament Graft Placement in Chronic Anterior Cruciate Deficient Knees [PDF]

, 2016
It is customary to perform medial meniscus repair before anterior cruciate ligament (ACL) graft placement when undertaken as a combined procedure. However, in chronic ACL-deficient knees, intraoperative anterior tibiofemoral translation can cause the ...
Grayson, Jane E., Vertullo, Christopher J., Wijenayake, Lahann   +2 more
core   +2 more sources