Results 51 to 60 of about 1,639,670 (236)

Anterior Cruciate Ligament Reconstruction With Preservation of Femoral Anterior Cruciate Ligament Stump [PDF]

Arthroscopy Techniques, 2014
Abstract Anterior cruciate ligament (ACL) reconstruction with preservation of either the remnant or the tibial stump is performed with the hope of improving the vascularization and proprioceptive function of the graft.
Hira Lal Nag, M.S.Orth., Himanshu Gupta, M.S.Orth.   +1 more
openaire   +3 more sources

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Evaluation of Functional Outcomes of Anterior Cruciate Ligament Reconstruction with Hamstring Autograft

Journal of Orthopedic and Spine Trauma
      INTRODUCTION: Anterior cruciate ligament is an intra-articular, extra synovial structure present in the central complex of the knee joint which along with other structures in the knee joint controls, limits motion and maintains static and dynamic ...
Mansi Jitendra Patel, Jaysinh Shambhu Cauhan, Lalit Bambhaniya, Tejas Jogi, Utkarsh Panchal, Aakash Koladiya, Neel Bhavsar   +6 more
doaj   +1 more source

Accelerating Musculoskeletal Robotics Through Parametric Design and 3D‐Printed Flexible Structures

Advanced Intelligent Systems, EarlyView.
Parametric design and flexible 3D printing create muscle‐, tendon‐, ligament‐, and cushion‐like robotic elements from a single thermoplastic polyurethane material. Tuning lattice patterns adjusts regional mechanical properties and enables coordinated multijoint motions in a life‐sized musculoskeletal leg under external suspension, with partial body ...
Shunnosuke Yoshimura, Kento Kawaharazuka, Kei Okada   +2 more
wiley   +1 more source

Computed Tomography‐Based Morphometric Analysis Reveals Intercondylar Notch Stenosis and Osteophytes Are Associated With Anterior Cruciate Ligament Injury

Arthroscopy, EarlyView.
Purpose To quantitatively assess intercondylar notch morphometrics using 3‐dimensional computed tomography reconstruction, evaluate their association with anterior cruciate ligament (ACL) injury in Asian populations, and investigate the prevalence of osteophytes in patients with ACL injury.
Xiaozhong Ma, WenMing Jiang, Chao Lu, Tongyue Ji, Su Yan, Heng Zhu, Xue He, Hao Shu, Lei Wang, Luning Sun   +9 more
wiley   +1 more source

Meniscal Ramp Lesions Are More Commonly Detected on Magnetic Resonance Imaging Than Arthroscopy in Patients With Anterior Cruciate Ligament Tears

Arthroscopy, EarlyView.
Purpose To assess the prevalence of, and factors associated with, meniscal ramp lesions in patients with anterior cruciate ligament (ACL) tears. Methods All patients who underwent primary ACL reconstruction (ACLR) during 2018 were evaluated. Preoperative magnetic resonance imaging (MRI) scans and surgical reports were reviewed searching for the ...
Erik Lerjefors, Riccardo Cristiani, Christoffer von Essen, Fredrik Johansson, Anders Stålman   +4 more
wiley   +1 more source

Editorial Commentary: May the Force Be With You—Preoperative Strength Is the Rotator Cuff Retear Predictor We Can Actually Train

Arthroscopy, EarlyView.
Abstract Predicting the clinical course of rotator cuff repairs is one of the most significant and unresolved challenges in shoulder surgery. Most established predictors of retear (e.g., advanced age, fatty infiltration, large tear size, and tendon retraction) are nonmodifiable—already set prior to the time the patient arrives in the operating room ...
Dustin J. Kress, Toufic R. Jildeh
wiley   +1 more source

Editorial Commentary: Are Intercondylar Notch Osteophytes Predictors of Anterior Cruciate Ligament Injuries?

Arthroscopy, EarlyView.
Abstract The cause of anterior cruciate ligament (ACL) tears is multifactorial. Intrinsic and extrinsic factors are known. Particularly, intrinsic factors can be analyzed and used to assess the potential risk of ACL injuries. Anatomical, hormonal, neuromuscular, and biomechanical determinants are described in this context.
Matthias Brockmeyer
wiley   +1 more source