Results 41 to 50 of about 1,741,997 (292)

Anterior Cruciate Ligament Reconstruction With Preservation of Femoral Anterior Cruciate Ligament Stump [PDF]

Arthroscopy Techniques, 2014
Abstract Anterior cruciate ligament (ACL) reconstruction with preservation of either the remnant or the tibial stump is performed with the hope of improving the vascularization and proprioceptive function of the graft.
Hira Lal Nag, M.S.Orth., Himanshu Gupta, M.S.Orth.   +1 more
openaire   +3 more sources

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Evaluation of Functional Outcomes of Anterior Cruciate Ligament Reconstruction with Hamstring Autograft

Journal of Orthopedic and Spine Trauma
      INTRODUCTION: Anterior cruciate ligament is an intra-articular, extra synovial structure present in the central complex of the knee joint which along with other structures in the knee joint controls, limits motion and maintains static and dynamic ...
Mansi Jitendra Patel, Jaysinh Shambhu Cauhan, Lalit Bambhaniya, Tejas Jogi, Utkarsh Panchal, Aakash Koladiya, Neel Bhavsar   +6 more
doaj   +1 more source

Metabolic‐Redox Remodeling of Inflammatory Synovium by Mannose‐Modified Selenium Nanoparticles for Osteoarthritis Therapy

Advanced Science, EarlyView.
Elevated GLUT1‐driven glycolysis and disrupted selenoprotein‐dependent redox homeostasis drive osteoarthritic progression. Intra‐articular mannose‐modified selenium nanoparticles (M‐SeNPs) selectively target hypermetabolic synovial cells to reprogram aberrant glycolysis and restore endogenous antioxidant defenses.
Yu‐Qing Zou, Chen‐Hao Xu, Bo‐Wei Li, Leung Chan, Yi‐Di Xu, Han‐Bo Su, Rui Peng, Fang‐Ji Luo, Ya‐Chen Peng, Zhen‐Yan Li, Vincent Kam Wai Wong, Xiao‐Fei Zheng, Xing Ma, Zhen‐Gang Zha, Tianfeng Chen, Huan‐Tian Zhang   +15 more
wiley   +1 more source

Combined Anterior Cruciate Ligament Reconstruction and Anterolateral Ligament Reconstruction With Hamstring Autograft Augmented With a Reinforced Bioinductive Scaffold. [PDF]

Arthrosc Tech
Abstract Combined anterior cruciate ligament and anterolateral ligament reconstruction is indicated for patients with anterior cruciate ligament rupture and preoperative rotatory instability. In smaller patients, the smaller graft diameter and shorter lengths of the gracilis and semitendinosus graft may not be sufficient for performing a combined ...
Wong CW, Lai CY, Wan KH, Lee RH, Ng EP.
europepmc   +2 more sources

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

Advanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu, Daming Liu, Haoxin Zhang, Zhiwei Qiao, Qiuming Gao, Jia Meng, Hongyin Yue, Songkai Li, Shuo Zhang, Tao Yuan, Yun Xue, Hui Jiang, Zhenguo Liu, Yibo Wang, Nirong Bao, Yuli Chen, Xiaojiang Yang   +16 more
wiley   +1 more source

Neuromuscular control and physical performance following anterior cruciate ligament reconstruction using a semitendinosus [PDF]

, 2006
Includes bibliographical ...
De Villiers, Elsje
core   +1 more source

Inframalleolar Harvest of Split‐Thickness Peroneus Longus Tendon Autograft for Anterior Cruciate Ligament Reconstruction [PDF]

Arthrosc Tech
Abstract The peroneus longus tendon has emerged as a viable autograft choice for single‐bundle anterior cruciate ligament reconstruction. However, ankle donor‐site morbidity remains a significant concern. More recently, the anterior half of the peroneus longus tendon has been suggested as an alternative graft to avoid possible ankle morbidity. However,
Haroun H, Mahmoud A, Elabd M.
europepmc   +2 more sources