Results 51 to 60 of about 112,976 (402)

Long noncoding RNA GCH1 mediates mitophagy via the PTEN‐induced kinase 1/Parkin pathway to drive chondrocyte dysfunction and cartilage degeneration in osteoarthritis

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract illustrates the role of lncRNA‐GCH1 in regulating mitophagy and its downstream effects on chondrocyte dysfunction and cartilage degradation in osteoarthritis (OA). Elevated lncRNA‐GCH1 stabilizes PINK1 protein, enhancing mitophagy and mitochondrial turnover.
Gang Zeng, Yujun Sun, Taihe Liu, Wenzhou Liu, Yanbo Chen, Jionglin Wu, Jiayuan Zheng, Weidong Song, Yue Ding   +8 more
wiley   +1 more source

Evaluation of Functional Outcomes of Anterior Cruciate Ligament Reconstruction with Hamstring Autograft

Journal of Orthopedic and Spine Trauma
      INTRODUCTION: Anterior cruciate ligament is an intra-articular, extra synovial structure present in the central complex of the knee joint which along with other structures in the knee joint controls, limits motion and maintains static and dynamic ...
Mansi Jitendra Patel, Jaysinh Shambhu Cauhan, Lalit Bambhaniya, Tejas Jogi, Utkarsh Panchal, Aakash Koladiya, Neel Bhavsar   +6 more
doaj   +1 more source

Effects of inclusion of proprioception training in the recovery of adults submitted to anterior cruciate ligament reconstruction surgery: a systematic review

Revista da Educação Física, 2020
Anterior cruciate ligament (ACL) rupture is an injury in young adults, triggering undesirable neuromuscular effects. A rehabilitation program is structured with exercises that aid in intensive care training, and proprioceptive training has been proposed ...
Wdson Donizete Da Silva Costa, Flávio Ricardo Guilherme, Stevan Ricardo dos Santos, Eduardo Gauze Alexandrino, Vânia Renata Guilherme, Wilson Rinaldi   +5 more
doaj   +1 more source

Anterior cruciate ligament reconstruction: principles of treatment

EFORT Open Reviews, 2016
Anterior cruciate ligament (ACL) reconstruction is one of the most common procedures in sports medicine. Several areas of controversy exist in ACL tear management which have engaged surgeons and researchers in debates towards identifying an ideal ...
N. Paschos, S. Howell
semanticscholar   +1 more source

Anterior cruciate ligament reconstruction

Journal of ISAKOS, 2016
Anterior cruciate ligament (ACL) reconstruction is a common procedure performed by orthopaedic surgeons, particularly in association with sports-related injuries. Over the past 10 years, a renewed interest in the native anatomy of the ACL has facilitated a progression from non-anatomic to more anatomic reconstruction techniques.
Sebastián Irarrázaval, Sebastián Irarrázaval, Moises Cohen, Masahiro Kurosaka, Freddie H. Fu   +4 more
openaire   +2 more sources

Impact differences among the landing phases of a drop vertical jump in soccer players [PDF]

, 2018
The aim of this study was to examine the differences of landing phase biomechanics between the players who had anterior cruciate ligament (ACL) reconstruction and healthy participants during single leg drop vertical jump. In this study, 11 soccer players
Akkaya, S., Alptekin, A., Celik, E., Kılıç, Özlem, Unver, F.   +4 more
core   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Knee Flexors Maximum Effective Angle Variation after Anterior Cruciate Ligament Reconstruction with Hamstring Graft

International Journal of Physiotherapy, 2021
Background: During the anterior cruciate ligament reconstruction, the graft is taken from the distal hamstring tendon, which causes morphological and neurological changes in these muscles, particularly on the maximum effective angle of the knee flexors ...
Hugues FRUYTIER, Jean MAZEAS, Maude TRAULLÉ, Amaury VANDEBROUCK, Pascal DUFFIET, Louis RATTE, Florian FORELLI   +6 more
doaj   +1 more source

Early Rehabilitation with Weight-bearing Standing-shaking-board Exercise in Combination with Electrical Muscle Stimulation after Anterior Cruciate Ligament Reconstruction [PDF]

, 2012
The objective of early rehabilitation after anterior cruciate ligament (ACL) reconstruction is to increase the muscle strength of the lower extremities. Closed kinetic chain (CKC) exercise induces co-contraction of the agonist and antagonist muscles. The
Fujii, Toshihiro, Hayashi, Masamichi, Kawamura, Kenji, Ozaki, Toshifumi, Takahashi, Kingo   +4 more
core   +1 more source

Sonographic Patellar and Quadriceps Tendon Length Pre‐ and Post‐Autograft Harvest: Reliability and Concurrent Validity

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Extensor mechanism autografts used for anterior cruciate ligament reconstruction, namely bone‐patellar tendon‐bone (BPTB) and quadriceps tendon (QT), may result in harvest‐site tendon elongation. Extended field of view (EFOV) ultrasound imaging has the potential to evaluate changes in tendon length, but the reliability and validity of these ...
Andrew Sprague, George Raum, Naoaki Ito
wiley   +1 more source