Results 71 to 80 of about 150,018 (308)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Surgical management of chronic Stevens-Johnson syndrome

Frontiers in Medicine
Stevens-Johnson Syndrome (SJS) is a rare but severe mucocutaneous disorder that often leads to chronic ocular complications, requiring a comprehensive and multidisciplinary approach to management.
Aastha Garg, Abha Gour, Nidhi Chauhan, Mehak Sapra, Virender Singh Sangwan   +4 more
doaj   +1 more source

Secretory Leukoprotease Inhibitor: A Native Antimicrobial Protein in the Innate Immune Response in a Rat Model of S. aureus Keratitis

Journal of Ophthalmology, 2009
Purpose. To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity in the innate immune reaction in a rat model of Staphylococcus aureus keratitis. Methods.
Victor E. Reviglio, Andres Grenat, Federico Pegoraro, Ruben H. Sambuelli, Tayyib Rana, Irene C. Kuo   +5 more
doaj   +1 more source

High-speed optical coherence tomography as a reliable adjuvant tool to grade ocular anterior chamber inflammation. [PDF]

, 2014
PURPOSE: To evaluate the high-speed anterior segment optical coherence tomography (AS-OCT) grading of the AS inflammation in patients with ocular inflammation. METHODS: A retrospective consecutive case series study.
Garg, Sunir, Igbre, Ann O, Rico, Mario C
core   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A NEW SPECIES OF MACROCENTRUS FROM NOVA SCOTIA (HYMENOP.) [PDF]

, 2017
Female.—Length 7 mm. Head very little wider than thorax, cheeks, viewed from the side, broader than the temples; face much broader than long, shallowly sparsely punctate; eyes large, prominent; malar space about as long as basal width of mandible ...
Daniel, Derrill M.
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Achondroplasia Associated with Bilateral Keratoconus

Case Reports in Ophthalmological Medicine, 2012
We report a rare case of bilateral keratoconus in association with achondroplasia. A 26-year-old male, with a known case of achondroplasia, complained of bilateral gradual deterioration in vision for the past few years.
Ammar M. Al Mahmood, Hind M. Al Katan, Ghada Y. Al Bin Ali, Samar A. Al-Swailem   +3 more
doaj   +1 more source

Refraction and eye anterior segment parameters in schizophrenic patients [PDF]

Arquivos Brasileiros de Oftalmologia, 2015
To evaluate the difference in terms of refractive errors and anterior segment parameters between schizophrenic patients and healthy volunteers.This study compared 70 patients (48 men) who were diagnosed with schizophrenia with a control group of 60 (35 men) who were similar in terms of age, gender, education, and socioeconomic level.
Cumurcu, Tongabay, Keser, Sinem, Cumurcu, Birgul Elbozan, Gunduz, Abuzer, Kartalci, Sukri   +4 more
openaire   +4 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source