Results 51 to 60 of about 247,139 (266)

Secretory Leukoprotease Inhibitor: A Native Antimicrobial Protein in the Innate Immune Response in a Rat Model of S. aureus Keratitis

Journal of Ophthalmology, 2009
Purpose. To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity in the innate immune reaction in a rat model of Staphylococcus aureus keratitis. Methods.
Victor E. Reviglio, Andres Grenat, Federico Pegoraro, Ruben H. Sambuelli, Tayyib Rana, Irene C. Kuo   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Changing Strategies in Keratoplasty After Corneal Hydrops: From Penetrating to Lamellar Approaches – A Narrative Review

Clinical Ophthalmology
Rafah Fairaq,1 Omar Kirat,1 Mohammed AlMutlak,1 Muhammad A Ahad,1 Omar Khan,1,2 Ahmed AlDayel,1 Saud Abdulbadie Khan,2 Mozon Alshareef,3 Wejdan Saeed Alghamdi,1 Halah Bin Helayel1 1Anterior Segment Division, King Khalid Eye Specialist Hospital, Riyadh ...
Fairaq R, Kirat O, AlMutlak M, Ahad MA, Khan O, AlDayel A, Khan SA, Alshareef M, Alghamdi WS, Bin Helayel H   +9 more
doaj  

Performance and Safety of a Sodium Hyaluronate, Xanthan Gum, and Osmoprotectants Ophthalmic Solution in the Treatment of Dry Eye Disease: An Observational Clinical Investigation

Ophthalmology and Therapy
Introduction Dry eye disease (DED) is characterized by an imbalance in the tear film, resulting in symptoms such as dryness, redness, and discomfort. The management of DED involves tear supplements, medications, or surgery in severe cases.
Mercedes Molero Senosiaín, Barbara Burgos-Blasco, Pilar Perez-García, Álvaro Sánchez-Ventosa, Marta Villalba-González, María Dolores López Pérez, José Carlos Díaz, Vanesa Díaz-Mesa, Alberto Villarrubia Cuadrado, Enrique Artiaga Elordi, Jose Manuel Larrosa Poves, Alejandro Blasco, Antonio Mateo, Claudine Civiale, Laura Bonino, Antonio Cano-Ortiz   +15 more
doaj   +1 more source

Self-inflicted eye injury

Annals of Saudi Medicine, 2017
Individuals with a factitious ocular disorder feign or exaggerate having an eye injury or intentionally produce an eye injury so as to assume the role of a sick person.
Mohammed A. Gogandy, Abdulqader Aljarad, Sabah S. Jastaneiah, Abdullah M. Alfawaz   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Comparison of Surgical Outcomes of Graft Survival Rate Using Surgeon Cut versus Precut DSAEK Tissue

Clinical Ophthalmology
Rawan Hawsawi,1 Rafah Fairaq,1 AbdulAziz Mohammed Alrabah,2 Mohammed Al Mutlak1 1Anterior Segment Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Eye Bank Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi ...
Hawsawi R, Fairaq R, Alrabah AM, Al Mutlak M   +3 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Outcomes of Repeat Deep Anterior Lamellar Keratoplasty in Keratoconus: Case Series

Clinical Ophthalmology
Omar Kirat,1 Rafah Fairaq,1 Mohammed AlMutlak,1 Raneem S AlQahtani,2 Ghadah A AlHussein,2 Sara AlHilali1 1Anterior Segment Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh, Saudi Arabia; 2Surgery Department, Aldiriyah Hospital ...
Kirat O, Fairaq R, AlMutlak M, AlQahtani RS, AlHussein GA, AlHilali S   +5 more
doaj