Results 111 to 120 of about 1,757,177 (283)

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

Advanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching, Hinako Ichikawa, Aya Motoyoshi, Shin Tanaka, Liam Morrow, Satoshi Shirae, Noriko Sakai, Shohei Kitahata, Michiko Mandai, Kazuaki Kadonosono   +9 more
wiley   +1 more source

Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber

Clinical Ophthalmology, 2012
Wael Soliman*, Ehab I Wasfi*, Omar M AliDepartment of Ophthalmology, Assiut University Hospital, Assiut University, Assiut, Egypt*These authors contributed equally to this workAim: To study the morphological pattern of pearl-like lesions in the anterior ...
Soliman W, Wasfi EI, Ali OM
doaj  

Toxic Anterior Segment Syndrome After Phacoemulsification

, 2013
Toxic anterior segment syndrome (TASS) caused by non-infectious agents is a sterile inflammation which occurs after anterior segment surgery and results in toxic damage to the intraocular tissues.
Gamze Dereli, Tamer Takmaz
core   +1 more source

Parameter Investigation for Stamp Manufacturing of Complex 3D Geometries Using Nanoimprint Lithography

Advanced Materials Technologies, EarlyView.
Nanoimprint lithography can replicate complex 3D microstructures with undercuts using single‐layer polymer stamps of different elasticities. By combining experiments and simulations, T‐shaped geometries and suitable undercut radii were identified that minimize stress and defects during demolding.
Christos Julianos Karapatzakis, Selina Burkert, Cordelia Friederike Wittemann, Andreas Heinrich   +3 more
wiley   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Comparison of Swept-Source Anterior Segment Ocular Coherence Tomography and Gonioscopy in Detecting Anterior Chamber Angle Closure [PDF]

Panhathai Yaisiri, Natthanose Panarojwongse, Isaraporn Treesit, Raveewan Choontanom, Ornwasee Jatuthong, Wallop Iemsomboon, Panrapee Funarunart Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok ...
Treesit I, Panarojwongse N, Iemsomboon W, Yaisiri P, Funarunart P, Jatuthong O, Choontanom R   +6 more
core  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Anterior Segment Optical Coherence Tomography in Corneal Diseases: Illustrative Clinical Compendium

TNOA Journal of Ophthalmic Science and Research
Anterior segment optical coherence tomography (AS-OCT) has revolutionised corneal disease evaluation by providing high-resolution, non-invasive cross-sectional imaging. This technology enables precise visualisation of corneal microstructure, quantitative
Raghav P. Peraka, Sudhakara R. Peraka, Neha Ghose   +2 more
doaj   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

Advanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio   +20 more
wiley   +1 more source