Results 91 to 100 of about 2,733,104 (305)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Therapeutic Advances in Ophthalmology, 2018 Purpose: This study compared the effectiveness of endothelial/Descemet’s membrane complex thickness obtained using high-definition anterior segment optical coherence tomography with endothelial cell density obtained using confocal microscopy as ...
Christopher Smith +7 more
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
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Cover, Content, and Editorial Note from Anterior J Vol. 18 No. 1 Desember 2018
, 2018 Assalamu’alaikum Wr. Wb.Dear reader, now ANTERIOR JURNAL re-published on Volume 18 Issue 1 December 2018. The success of this publication is the result of good cooperation of all parties who maintain the publishing sustainability twice a year ...
Anterior Jurnal, Chief Editor of
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
New IOL formula using anterior segment three-dimensional optical coherence tomography.
PLoS ONE, 2020 This retrospective study was aimed to compare prediction errors from various combinations of biometric data generated using optical coherence tomography (OCT) and develop a new intraocular lens (IOL) formula using biometric data.
Young-Sik Yoo +4 more
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Anterior-segment morphology and corneal biomechanical characteristics in pigmentary glaucoma
, 2013 Annemarie Klingenstein, Marcus Kernt, Florian Seidensticker, Anselm Kampik, Christoph HirneissDepartment of Ophthalmology, University of Munich Hospital, Ludwig-Maximilians University, Munich, GermanyPurpose: The aim of the study reported here was to ...
Hirneiss C +4 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Influence of diabetes mellitus on anterior segment of the eye
, 2018 Sang Beom Han,1 Hee Kyung Yang,2 Joon Young Hyon2 1Department of Ophthalmology, School of Medicine, Kangwon National University, Kangwon National University Hospital, Chuncheon, Korea; 2Department of Ophthalmology, Seoul National University Bundang ...
Hyon JY, Han SB, Yang HK
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Correlation of Anterior Segment Parameters in Keratoconus Patients
International Journal of Keratoconus and Ectatic Corneal Diseases, 2012 ABSTRACT Purpose To evaluate the corneal asphericity, volume, thickness and keratometry and the correlation among these variables in keratoconus patients. Materials and methods A total of 1,071 eyes of 810 patients diagnosed with keratoconus were evaluated with a Pentacam (Oculus Optikgerate GmbH).
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