Results 71 to 80 of about 5,568,025 (289)

Evaluation of Epithelial Downgrowth Using Anterior Segment Optical Coherence Tomography: A Case Report

open access: yes, 2013
Epithelial downgrowth is a rare, sight-threatening complication which can develop following anterior segment surgeries with corneal incisions. However, due to translucent nature of epithelial membrane and diversity of clinical signs, epithelial ...
Alime Güneş   +5 more
core   +1 more source

Comparison of Refractive Status and Anterior Segment Parameters of Juvenile Open-Angle Glaucoma and Normal Subjects [PDF]

open access: yes, 2018
Objectives:Our aim was to compare the refractive status and anterior segment parameters of patients with juvenile open-angle glaucoma (JOAG) and normal subjects.Materials and Methods:Twenty-five recently diagnosed cases of JOAG and 24 normal subjects ...
Pelin Yılmazbaş   +3 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Identifying the critical factors that influence intraocular pressure using an automated regression tree

open access: yesAfrican Vision and Eye Health, 2017
Background: Assessment of intraocular pressure (IOP) is an important test in glaucoma. In addition, anterior segment variables may be useful in screening for glaucoma risk.
Nishanee Rampersad, Rekha Hansraj
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Anterior segment optical coherence tomography: A clinically-oriented atlas

open access: yes
Anterior Segment Optical Coherence Tomography: A Clinically-Oriented Atlas introduces a wide range of clinical applications of anterior segment OCT for the diagnosis, follow up, and assessment of medical and surgical treatments and critical interventions.
Akova, Berna   +2 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Pediatric cornea and anterior segment imaging

open access: yes
As a noninvasive, well-tolerated imaging modality, anterior segment optical coherence tomography (AS-OCT) can be instrumental for visualization of pediatric cornea, ocular surface, and anterior segment abnormalities.
Ali, Asim, Zhu, Angela Y.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Bimanual anterior segment revision surgery for anterior capsule contraction syndrome associated with anterior flexion of intraocular lens haptics

open access: yes, 2013
PURPOSE To report the incidence of anterior capsule contraction syndrome (ACCS) and to present a novel minimally invasive bimanual technique for anterior segment revision surgery associated with ACCS with anterior flexion of the intraocular lens ...
Zinkernagel, Martin   +5 more
core   +1 more source

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