Results 91 to 100 of about 2,368,105 (199)

Modified anterior temporal lobectomy: anatomical landmarks and operative technique

, 2016
There is great controversy about which surgical approach is the most selective and efficient for resection of mesial structures of the temporal lobe for treatment of mesial temporal lobe epilepsy. Selective approaches have been described in an attempt to
Almeida, J. P., Joaquim, Andrei F., Campos, Brunno M. de, Tedeschi, Helder, Ghizoni, Enrico, Cendes, Fernando, Yasuda, Clarissa L.   +6 more
core   +1 more source

Association between temporal lobe P-glycoprotein expression and seizure recurrence after surgery for pharmacoresistant temporal lobe epilepsy

Neurobiology of Disease, 2010
Surgery is recommended for pharmacoresistant temporal lobe epilepsy (TLE), but seizures recur in approximately one third of patients postsurgery.
Patrick Kwan, Hiu Ming Li, Eman Al-Jufairi, Rawia Abdulla, Michael Gonzales, Andrew H. Kaye, Cassandra Szoeke, Ho Keung Ng, Ka Sing Wong, Terence J. O'Brien   +9 more
doaj   +1 more source

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre‐existing and de novo postoperative depression

Epileptic Disorders, Volume 28, Issue 5, Page 1554-1566, October 2026.
Abstract Objective Depression is common in mesial temporal lobe epilepsy (mTLE), but its neuroanatomical basis—and overlap with major depressive disorder (MDD)—remains poorly defined. We investigated whether the cortical and subcortical alterations reported in MDD are also present in mTLE and leveraged the frequent occurrence of depression after ...
Philip Fink‐Jensen, Brice Ozenne, Ane Kloster, Bo Jespersen, Kirsten Vinter, Guido Rubboli, Martin Balslev Jørgensen, Sandor Beniczky, Melanie Ganz, Lars Hageman Pinborg   +9 more
wiley   +1 more source

The Cessation of Continuous Spike Wave in Slow-Wave Sleep Following a Temporal Lobectomy

, 2011
The role of surgery in continuous spike wave in slow-wave sleep has not been robustly explored. The authors present a case of an 11-year-old boy with refractory partial seizures and continuous spike wave in slow-wave sleep who was treated with an ...
Radhika Dhamija, Brian D. Moseley, Elaine C. Wirrell   +2 more
core   +1 more source

Effect of time to palliative epilepsy surgery on outcomes

Epilepsia, Volume 67, Issue 10, Page 5189-5200, October 2026.
Abstract Objective Epilepsy duration is a modifiable risk factor in the outcome of definitive epilepsy surgery; however, an analogous effect in palliative procedures has not been shown. We reviewed the Pediatric Epilepsy Surgery Database data for an association between epilepsy duration and seizure reduction in palliative procedures.
Robert M. Crutcher, David E. Horvat, Avery R. Caraway, Kristen H. Arredondo, Taylor J. Abel, Nitin Agarwal, Allyson L. Alexander, Dallas Michael Armstrong, Kurtis I. Auguste, Danilo Bernardo, Jeffrey Bolton, David Bonda, Dewi Frances Depositario‐Cabacar, Krista Eschbach, William D. Gaillard, Aran Groves, Jason S. Hauptman, Pradeep K. Javarayee, Cemal Karakas, Andrew T. Knox, Jenny J. Lin, Patricia E. McGoldrick, Derryl J. Miller, Edward John Novotny, Adam P. Ostendorf, Pilar D. Pichon, Shilpa B. Reddy, Debopam Samanta, Rani K. Singh, Janelle L. Wagner, Steven M. Wolf, Lily C. Wong‐Kisiel, Fernando N. Galan, M. Scott Perry, Michael A. Ciliberto   +34 more
wiley   +1 more source

Preoperative amygdala fMRI in temporal lobe epilepsy [PDF]

, 2009
Purpose: Anterior temporal lobe resections (ATLR) benefit 70% of patients with refractory mesial temporal lobe epilepsy (TLE), but may be complicated by emotional disturbances.
Silvia B. Bonelli, Mahinda Yogarajah, Matthias J. Koepp, John S. Duncan, Mark R. Symms, Koepp, M.J., Robert Powell, Powell, R., Thompson, P. J., Duncan, J.S., Symms, M.R., Bonelli, S.B., Yogarajah, M., Pamela J. Thompson   +13 more
core   +1 more source

Complete lesion resection and early surgical intervention are favorable factors for long‐term seizure freedom in drug‐resistant epileptic spasms

Epilepsia Open, Volume 11, Issue 5, Page 1541-1555, October 2026.
Abstract Objective Epileptic spasms (ES) in children carry a high risk of neurodevelopmental delay, yet predictors of long‐term surgical outcome remain incompletely defined. This study aimed to evaluate seizure outcomes following epilepsy surgery and to identify independent prognostic factors for postoperative recurrence.
Hua Li, Yao Wang, Qiang Guo, Junxi Chen, Kaihui Li, Danfang Li, Qinghua Tan, Jing Guo   +7 more
wiley   +1 more source

A prospective study of the effects of anterior temporal lobectomy on emotion recognition and theory of mind

, 2007
Nineteen patients evaluated facial emotional expressions and performed 'theory of mind' reasoning tasks before and after a temporal lobectomy for medically intractable epilepsy, and results were compared with the performance of 19 healthy controls ...
David, A S, Shaw, P, Radbourne, C, Lawrence, E, Bramham, J, Brierley, B   +5 more
core   +1 more source

Psychiatric Symptoms Following Anterior Temporal Lobectomy.

Journal of the Japan Epilepsy Society, 1995
難治側頭葉てんかんのため本院で手術を受け1年以上経過した22例の患者について術後の精神症状を検討した。その結果, (1) 術前に精神病状態を体験したことのない患者で術後新規に精神病状態を体験した患者が3例あり, いずれも右切除例であった, (2) 際立った精神症状をきたした患者では, 実体的意識性, 夢様状態を前兆とするものが比較的多かった, (3) うつ状態は術後3カ月以内には出現し, 時には自殺企図を伴うほど重症になった, (4) 術前に敵意・攻撃性が目立った患者は, 術後には改善がみられた, (5) 精神症状の大部分は1年以内には消失したが, 軽症化したものの2年以上遷延した例が2例みられた。以上の結果を文献例と比較し, 術後精神病を心因論だけからは説明することが難しいことを指摘するとともに,
Kanemoto, Kousuke, Kawasaki, Jun, Takeuchi, Juji, Kawai, Itsuo   +3 more
openaire   +2 more sources

The spatial learning task of Lhermitte and Signoret: Marker of bilateral hippocampal dysfunction in temporal lobe epilepsy

Epilepsia Open, Volume 11, Issue 5, Page 1773-1785, October 2026.
Abstract Objective Bilateral hippocampal compromise in temporal lobe epilepsy (TLE) substantially increases the risk of significant adverse memory outcomes following unilateral anterior temporal lobectomy and may contraindicate surgery. The Spatial Learning Task (SLT) of Lhermitte and Signoret (1972) is a simple object–location arbitrary associative ...
Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby   +6 more
wiley   +1 more source