Results 101 to 110 of about 48,019 (211)

Beyond Broca and Wernicke: Epilepsy surgery in the language areas

Epileptic Disorders, Volume 28, Issue 3, Page 581-601, June 2026.
Abstract Epilepsy surgery in language areas is challenged by the intricacies of presurgical workup and surgical planning. In recent decades, the view of language‐related circuitry has shifted from being localized in a few cortical centers to a distributed, dynamically interconnected system, increasing complexity.
Carmen Barba, Alessandro De Benedictis, Veronica Pelliccia, Domenico Tortora, Federico Melani, Alessandro Consales, Domenica Immacolata Battaglia, Elisabetta Cesaroni, Lorenzo Ferri, Alice Noris, Matteo Pugnaghi, Michele Rizzi, Giuseppe Bertini, Flavio Villani, Laura Tassi, on behalf of Commission of Epilepsy Surgery, Italian League against Epilepsy   +16 more
wiley   +1 more source

Indication for Anterior Temporal Lobectomy in Patients with Temporal Lobe Epilepsy and Psychopathology [PDF]

Epilepsia, 2000
Summary: The chronicity and severity of epilepsy, as well as the presence of temporal lobe foci, appear to correlate with psychopathology. A high prevalence of psychopathology has been reported among patients who are candidates for anterior temporal lobectomy (ATL).
openaire   +2 more sources

Evaluating the task‐specificity model of verbal memory: Regional volumetric analyses in temporal lobe epilepsy with hippocampal sclerosis

Epilepsia Open, Volume 11, Issue 3, Page 764-776, June 2026.
Abstract Objective Verbal memory tasks differ in their cognitive demands and may rely on distinct left medial temporal structures. One model holds that verbal delayed recall is hippocampal dependent, whereas verbal paired associate learning relies on adjacent rhinal cortex.
Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Heath R. Pardoe, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby   +7 more
wiley   +1 more source

Temporopolar epilepsy stereoEEG: implant technique and outcomes

Epilepsy & Behavior Reports
The temporal pole (TP) is an under-investigated region in temporal lobe epilepsy, often overlooked during stereoEEG (sEEG) due to the lack of characteristic Phase 1 findings and technical limitations in implanting using traditional orthogonal ...
Maya A. Jayaram, Andrew I. Yang, Ashley L.B. Raghu, Peter A. Rozman, Denise F. Chen, Jon T. Willie, Ammar Kheder, Robert E. Gross   +7 more
doaj   +1 more source

Microelectrode array scaled for human hippocampal slices

Epilepsia Open, Volume 11, Issue 3, Page 777-786, June 2026.
Abstract Objective Temporal lobe epilepsy (TLE) is characterized by recurrent seizures originating usually from the hippocampus, and approximately one‐third of TLE patients remain refractory to pharmacological interventions. Surgical resection offers a potential cure for refractory TLE cases, with approximately 70% achieving seizure freedom. Still, the
Anssi Pelkonen, Vera Lezhneva, Tomi Ryynänen, Joose Kreutzer, Valeriia Sitnikova, Mireia Gómez‐Budia, Adriana Della Pietra, Antonios Dougalis, Jenni Kyyriäinen, Mastaneh Torkamani‐Azar, Henri Eronen, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Alejandra Sierra, Reetta Kälviäinen, Tarja Malm   +16 more
wiley   +1 more source

Epilepsy Surgery for Skull-Base Temporal Lobe Encephaloceles: Should We Spare the Hippocampus from Resection?

Brain Sciences, 2018
The neurosurgical treatment of skull base temporal encephalocele for patients with epilepsy is variable. We describe two adult cases of temporal lobe epilepsy (TLE) with spheno-temporal encephalocele, currently seizure-free for more than two years after ...
Firas Bannout, Sheri Harder, Michael Lee, Alexander Zouros, Ravi Raghavan, Travis Fogel, Kenneth De Los Reyes, Travis Losey   +7 more
doaj   +1 more source

Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis

Epilepsia Open, Volume 11, Issue 3, Page 692-701, June 2026.
Abstract Epilepsy surgery is an established treatment for drug‐resistant epilepsy, offering a realistic prospect of seizure freedom in well‐selected candidates. However, surgery is sometimes offered to individuals with a low probability of seizure freedom when it is framed as potentially “life‐saving” on the basis of the elevated mortality associated ...
Sallie Baxendale, Dominic Heaney, Matthew C. Walker   +2 more
wiley   +1 more source

Association between temporal lobe P-glycoprotein expression and seizure recurrence after surgery for pharmacoresistant temporal lobe epilepsy

Neurobiology of Disease, 2010
Surgery is recommended for pharmacoresistant temporal lobe epilepsy (TLE), but seizures recur in approximately one third of patients postsurgery.
Patrick Kwan, Hiu Ming Li, Eman Al-Jufairi, Rawia Abdulla, Michael Gonzales, Andrew H. Kaye, Cassandra Szoeke, Ho Keung Ng, Ka Sing Wong, Terence J. O'Brien   +9 more
doaj   +1 more source

Individual Memory Change After Anterior Temporal Lobectomy: A Base Rate Analysis Using Regression‐Based Outcome Methodology [PDF]

, 1998
Roy C. Martin, Stephen M. Sawrie, David L. Roth, Frank Gilliam, Edward Faught, Richard B. Morawetz, Ruben Kuzniecky   +6 more
openalex   +1 more source

Regional hippocampal diffusion abnormalities associated with subfield‐specific pathology in temporal lobe epilepsy

Epilepsia Open, 2019
Objective Hippocampal sclerosis (HS) is the most common pathology and best predictor of surgical outcome for medically refractory patients with temporal lobe epilepsy (TLE).
Sarah Treit, Graham Little, Trevor Steve, Tom Nowacki, Laura Schmitt, B. Matt Wheatley, Christian Beaulieu, Donald W. Gross   +7 more
doaj   +1 more source