Results 181 to 190 of about 2,061,103 (249)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

Clinical Outcomes After Catheter Ablation in Patients With Structural Heart Disease and Ventricular Fibrillation

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction In patients with ischemic cardiomyopathy (ICM), recurrent VF may be treated with catheter ablation by targeting triggering premature ventricular complexes (PVCs) and/or ventricular scar homogenization. Data on optimal ablation strategies in patients with non‐ischemic cardiomyopathy (NICM) remain limited.
Kenji Hashimoto   +2 more
wiley   +1 more source

Learning Curve of Pentaspline Pulsed‐Field Ablation With Posterior Wall Isolation for Persistent Atrial Fibrillation

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pentaspline pulsed‐field ablation (PFA) has emerged as a novel modality for pulmonary vein isolation (PVI) and posterior wall isolation (PWI) in persistent atrial fibrillation (AF). However, the learning curve associated with combined PVI + PWI and the contribution of anatomical factors to acute lesion completeness remain ...
Atsuhiko Yagishita   +5 more
wiley   +1 more source

Cardiac structure and function in psoriasis: A cross‐sectional analysis of the PSOCADIA study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Individuals with well‐treated psoriasis exhibited a higher burden of myocardial dysfunction (GLS < 16%) compared with controls, independent of cardiometabolic comorbidity. The prevalence was similar across psoriasis severity, highlighting the importance of cardiovascular assessment in all patients with psoriasis. Abstract Background Psoriasis is linked
Maria Dons   +16 more
wiley   +1 more source

Genetic Susceptibility to Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

open access: yesJournal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa   +5 more
wiley   +1 more source

Leadless Pacemaker Implantation in High‐Risk Patients: Real‐World Outcomes From a Multicenter Israeli Registry

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Transvenous pacemakers are effective but carry significant short‐ and long‐term complications. Leadless pacemakers were developed to overcome these limitations, however, data in high‐risk patients ineligible for transvenous systems remain limited.
Moshe Katz   +7 more
wiley   +1 more source

Ventricular Synchrony in Targeted Right Ventricular Septal Pacing: A Prospective Paired Comparison to Apical Placement

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background/Objectives Right ventricular (RV) apical pacing, the standard pacing approach, often induces ventricular dyssynchrony, potentially impairing cardiac function. This study aims to investigate whether targeted RV septal pacing, guided by functional electrophysiological feedback during implantation, reduces ventricular dyssynchrony ...
Bianca Iulia Catrina   +5 more
wiley   +1 more source

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