Results 201 to 210 of about 2,061,103 (249)

Clearance of p16‐positive cardiac cells improves age‐related cardiac remodeling in mice

Experimental Physiology, EarlyView.
Abstract Senescent cells are characterized by expression of markers like p16 and secretion of profibrotic and proinflammatory factors. The role of cellular senescence in age‐related cardiac remodeling and dysfunction is incompletely understood. This study aimed to: (i) evaluate the effect of p16‐ positive cell clearance on cardiac function and ...
Mozhdeh Mehdizadeh, Martin Mackasey, Kimia Gharagozloo, Martin Aguilar, Patrice Naud, Allan Ochs, Nhung Vuong‐Robillard, Eric Thorin, Gerardo Ferbeyre, Jean‐Claude Tardif, Martin G. Sirois, Jean Francois Tanguay, Stanley Nattel   +12 more
wiley   +1 more source

A Case Report of Myocardial Infarction Complicated With Blood Pressure Fluctuations Caused by Pheochromocytoma. [PDF]

J Clin Hypertens (Greenwich)
Li H, Yang W, Feng Y, Zhang Y, Yan G, Gao C.   +5 more
europepmc   +1 more source

Sex differences in macrovascular responsiveness: Acute effects of hot water immersion versus aerobic exercise in overweight older adults

Experimental Physiology, EarlyView.
Abstract Recent studies have focused on the potential benefits of heat exposure for cardiovascular health. However, the acute effects of heat therapy on conduit arteries remain unclear, particularly in overweight and obese older males and females. This study aimed to compare core temperature (Tc), heart rate (HR), and brachial, femoral, and carotid ...
Juliene G. Costa, Joao Carlos Locatelli, Kristanti W. Wigati, Louise H. Naylor, Andrew Haynes, Helen Jones, Daniel J. Green   +6 more
wiley   +1 more source

Assessment of Left Ventricular Systolic Dysfunction in Patients Undergoing Primary Percutaneous Coronary Intervention for Anterior Wall ST-Segment Elevation Myocardial Infarction After 48 Hours in the Cardiac Emergency. [PDF]

Cureus
Raees A, Raees A, Chattha AT, Flogaitis I.   +3 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Cardiomegaly of Unknown Origin: Why Morphology Still Matters in the Genetic Era - A Case of Cardiac Fabry Disease. [PDF]

Medeni Med J
Makarov I, Roy Y, Mitrofanova L.
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Serum periostin levels in myocardial infarction: Findings from forensic autopsy cases. [PDF]

PLoS One
Yamada A, Unuma K, Kitamura O.
europepmc   +1 more source

Multiscale four‐dimensional imaging of cardiac remodelling after myocardial infarction

The Journal of Physiology, EarlyView.
Abstract figure legend Multiscale 4D imaging framework for integrated phenotyping of post‐infarction remodelling. Myocardial infarction triggers dynamic changes across mechanical, haemodynamic and biological axes, progressing from acute injury and inflammation to extracellular matrix remodelling and scar maturation.
Hanzhou Lei, Boris Martinac, Yang Guo
wiley   +1 more source

Left circumflex myocardial infarction. [PDF]

CMAJ
Kiflen M, Grami N, Alnasser S.
europepmc   +1 more source