Results 31 to 40 of about 27,999 (213)

Systemic Toxicity of L‐Mimosine in Rabbits: A Non‐Rodent Model for Safety Assessment

Journal of Applied Toxicology, EarlyView.
ABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
S. M. Ferreira, H. Zapparoli, C. S. Mussi, P. C. Maiorka, A. F. C. Andrade, S. L. Górniak, A. T. Gotardo   +6 more
wiley   +1 more source

Milk quality parameters associated with the occurrence of veterinary drug residues in bulk tank milk

Scientia Agricola
Veterinary drug residues in bulk tank milk are important to all sectors of the dairy chain because they are one of the major factors which determine the safety of the final product.
Lidia Cristina Almeida Picinin, Isabela Maia Toaldo, Rodrigo Barcellos Hoff, Fernando Nogueira Souza, Mônica Oliveira Leite, Leorges Moraes Fonseca, Soraia Araújo Diniz, Marcos Xavier Silva, João Paulo Amaral Haddad, Mônica Maria Oliveira Pinho Cerqueira, Marilde Terezinha Bordignon-Luiz   +10 more
doaj   +1 more source

Changes in the Diversity and Composition of Gut Microbiota of Red-Crowned Cranes (Grus japonensis) after Avian Influenza Vaccine and Anthelmintic Treatment

Animals, 2022
Gut microbiota homeostasis is important for host health and well-being; however, drugs may affect the composition and function of the gut microbiota. Red-crowned cranes are a vulnerable species.
Xinyi Zhao, Wentao Ye, Wei Xu, Nan Xu, Jiajun Zheng, Rong Chen, Hongyi Liu   +6 more
doaj   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, EarlyView.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A

Pharmaceutics, 2020
Novel-antibiotics are urgently needed to combat an increase in morbidity and mortality due to resistant bacteria. The preclinical candidate corallopyronin A (CorA) is a potent antibiotic against Gram-positive and some Gram-negative pathogens for which a ...
Anna K. Krome, Tim Becker, Stefan Kehraus, Andrea Schiefer, Christian Steinebach, Tilman Aden, Stefan J. Frohberger, Álvaro López Mármol, Dnyaneshwar Kapote, Rolf Jansen, Lillibeth Chaverra-Muñoz, Marc P. Hübner, Kenneth Pfarr, Thomas Hesterkamp, Marc Stadler, Michael Gütschow, Gabriele M. König, Achim Hoerauf, Karl G. Wagner   +18 more
doaj   +1 more source

Spectroscopic, X‐Ray Crystallographic, and Hirshfeld Surface Analyses for the Investigation of Intermolecular Interactions in Carboxamide Hydrazone Hybrids

ChemistryOpen, EarlyView.
Two novel carboxamide hydrazone hybrids are synthesized and characterized. Structural, spectroscopic, and computational analyses reveal dominant hydrogen bonding, π–π stacking, and reactive sites. Compound 2b exhibits potent antibacterial activity against Staphylococcus aureus, highlighting its potential as a cost‐effective therapeutic agent.
Nabila A. Kheder, Mostafa E. Salem, Saied M. Soliman, Ismail A. Elhaty, Naglaa S. Mahmoud, Mohamed Abdel‐Megid, Kamal M. Dawood   +6 more
wiley   +1 more source

Nematicidal Effect and Histological Modifications Induced by Hydrolysable Tannin Extract on the Third-Stage Infective Larvae of Haemonchus contortus

Biology, 2020
Haemonchus contortus is the most frequent and most important nematode parasite in the ruminants production of tropical and subtropical regions. There are strains resistant to all families of available anthelmintics.
Perla María del Carmen Acevedo-Ramírez, Claudia Hallal-Calleros, Iván Flores-Pérez, Fernando Alba-Hurtado, María Berenit Mendoza-Garfias, Rubén Barajas   +5 more
doaj   +1 more source

Acaricidal activity of small molecule antagonists of the tick kinin receptor against Rhipicephalus microplus acaricide‐susceptible and resistant strains

Pest Management Science, EarlyView.
Two small molecules, SACC‐0039590 and SACC‐0428788, killed cattle fever tick, R. microplus, susceptible Deutch strain and pyrethroid resistant Arauquita strain larvae. SACC‐0039590 at 1 mM decreased the reproductive parameters of Deutch females. Abstract BACKGROUND Resistance to acaricides underscores the need for tick control alternatives.
Waleed M. Arafa, Kimberly H. Lohmeyer, Patricia V. Pietrantonio   +2 more
wiley   +1 more source

Antiparasitic activity of the steroid-rich extract of Schima wallichii against poultry cestode [PDF]

Veterinary World
Background and Aim: Schima wallichii Korth., commonly known as the needlewood tree (family Theaceae) has therapeutic uses in traditional Mizo medicine for human helminthiasis and serves as a balm against ectoparasites in animals.
Pawi Bawitlung Lalthanpuii, Kholhring Lalchhandama   +1 more
doaj   +1 more source

In Vitro Potential of the Acetone Leaf Extract and Fractions of Psychotria capensis (Eckl.) Vatke (Rubiaceae) to Combat Co-Infection of Tuberculosis and Helminthiasis

Frontiers in Pharmacology, 2022
Tuberculosis (TB) is a disease of global importance that affects millions of people. Approximately a quarter of the world’s population is currently infected with M.
Abimbola O. Aro, Ibukun M. Famuyide, Ademola A. Oyagbemi, Prudence N. Kabongo-Kayoka, Lyndy J. McGaw   +4 more
doaj   +1 more source