Results 41 to 50 of about 60,851 (310)

The Anthelmintic Activity of Nepeta racemosa Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies

Pathogens
Gastrointestinal nematodes (GINs) inflict significant economic losses on sheep and goat farming globally due to reduced productivity and the development of anthelmintic resistance.
Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol   +6 more
doaj   +1 more source

Chemical Profile and Biological Activities of Essential Oil from Artemisia vulgaris L. Cultivated in Brazil

Pharmaceuticals, 2019
Essential oil from the leaves of Artemisia vulgaris L. (Compositae) cultivated in Brazil was investigated for its chemical composition and biological activities including antibacterial, antifungal, and anthelmintic.
Sonia Malik, Ludmilla Santos Silva de Mesquita, Carolina Rocha Silva, José Wilson Carvalho de Mesquita, Emmeline de Sá Rocha, Jayakumar Bose, Rambod Abiri, Patricia de Maria Silva Figueiredo, Livio M. Costa-Júnior   +8 more
doaj   +1 more source

Quantification of cure for pharmacodynamic models of antimalarial drugs: Deterministic versus stochastic approaches

British Journal of Clinical Pharmacology, EarlyView.
In silico pharmacokinetic–pharmacodynamic (PK–PD) models are used to inform dose optimisation in antimalarial drug development. Here the PK–PD models capture the change in parasite count over time because of exposure to antimalarial drug(s). For current deterministic PD models, simulated parasite numbers decline proportionally during treatment ...
Meg K. Tully, Robert J. Commons, Julie A. Simpson, David J. Price   +3 more
wiley   +1 more source

Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes

Molecules, 2020
Soil-transmitted nematodes (STN) infect 1–2 billion of the poorest people worldwide. Only benzimidazoles are currently used in mass drug administration, with many instances of reduced activity. Terpenes are a class of compounds with anthelmintic activity.
Zeynep Mirza, Ernesto R. Soto, Yan Hu, Thanh-Thanh Nguyen, David Koch, Raffi V. Aroian, Gary R. Ostroff   +6 more
doaj   +1 more source

Moxidectin: A Viable Alternative for the Control of Ivermectin-Resistant Gastrointestinal Nematodes in Beef Cattle

Acta Veterinaria, 2022
The increasing prevalence of anthelmintic resistance in cattle especially for avermectins, is a challenge for controlling parasites in some herds. Thus, field studies demonstrating the increase in productivity by the use of anthelmintic formulations ...
Borges Dyego Gonçalves Lino, Conde Mário Henrique, Cunha Cibele Cristina Tavares, De Freitas Mariana Green, Moro Elio, De Almeida Borges Fernando   +5 more
doaj   +1 more source

Activity Against Pythium insidiosum and Isolated Constituents of Cordia insignis Roots

Chemistry &Biodiversity, EarlyView.
This study investigates the roots of Cordia insignis in search of novel treatments for pythiosis, caused by the oomycete Pythium insidiosum. Seven compounds are isolated, including steroids, a saponin, a coumarin, a fatty acid, and a glycoside, the latter two are reported for the first time in the genus.
Rennan Carlos de Oliveira, Kheytiany Hellen da Silva Lopes, Mariele Rondon Santos Gonçalves, Mario Geraldo de Carvalho, Yasmin Sena de Amorin Dias da Silva, Leonardo Gomes de Vasconcelos, Paulo Teixeira de Sousa Júnior, Ivana Maria Póvoa Violante, Tereza Auxiliadora Nascimento Ribeiro   +8 more
wiley   +1 more source

Milk quality parameters associated with the occurrence of veterinary drug residues in bulk tank milk

Scientia Agricola
Veterinary drug residues in bulk tank milk are important to all sectors of the dairy chain because they are one of the major factors which determine the safety of the final product.
Lidia Cristina Almeida Picinin, Isabela Maia Toaldo, Rodrigo Barcellos Hoff, Fernando Nogueira Souza, Mônica Oliveira Leite, Leorges Moraes Fonseca, Soraia Araújo Diniz, Marcos Xavier Silva, João Paulo Amaral Haddad, Mônica Maria Oliveira Pinho Cerqueira, Marilde Terezinha Bordignon-Luiz   +10 more
doaj   +1 more source

Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro

Molecules, 2020
Kava extract, an aqueous rhizome emulsion of the plant Piper methysticum, has been used for centuries by Pacific Islanders as a ceremonial beverage, and has been sold as an anxiolytic agent for some decades.
H.M.P. Dilrukshi Herath, Aya C. Taki, Nghi Nguyen, José Garcia-Bustos, Andreas Hofmann, Tao Wang, Guangxu Ma, Bill C.H. Chang, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser   +10 more
doaj   +1 more source

Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota [PDF]

, 2013
Background: The soil-transmitted helminth (STH), Trichuris trichiura colonises the human large intestine where it may modify inflammatory responses, an effect possibly mediated through alterations in the intestinal microbiota.
A Olsen, AJ Bancroft, AL Kau, AL Moncayo, Alan W. Walker, AW Walker, C De Filippo, C Quince, CA Figueiredo, DA Bundy, EG Zoetendal, EK Costello, GD Wu, H Sokol, J Bethony, J Maukonen, JL Shin, Jorge Reyes, JS Crowther, Julian Parkhill, KS Hayes, LC Rodrigues, LS Mansfield, M Reina Ortiz, Maritza Vaca, Martha Chico, MI Bahl, MJ Broadhurst, MP Bryant, N Segata, P Endara, P Steinmann, PB Eckburg, PD Schloss, Philip Cooper, RW Li, RW Li, RW Summers, RW Summers, S Wu, ST Walk, Stefan Bereswill, Susannah J. Salter, T Yatsunenko, TT MacDonald, VB Young, Y Suputtamongkol   +46 more
core   +6 more sources

Chemical and Biological Properties of Hymenaea courbaril L.: A Review

Chemistry &Biodiversity, EarlyView.
PRISMA‐style flowchart showing the screening process of studies identified and selected in the review has been added to the attachments. ABSTRACT Hymenaea courbaril L., commonly known as jatobá, is a plant traditionally used by native populations for medicinal purposes, in addition to providing edible fruits and durable wood for construction.
Cicera Alane Coelho Gonçalves, Geane Gabriele de Oliveira Souza, Ana Maria Fernandes Duarte, Joice Barbosa do Nascimento, Fázia Fernandes Galvão Rodrigues, José Galberto Martins da Costa, Fabíola Fernandes Galvão Rodrigues   +6 more
wiley   +1 more source