Results 31 to 40 of about 18,966 (200)

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Atividade anti-helmíntica do extrato aquoso das folhas de Zanthoxylum rhoifolium Lam. (Rutaceae) Anthelmintic activity of aqueous extract of Zanthoxylum rhoifolium Lam. leaves (Rutaceae)

Revista Brasileira de Parasitologia Veterinária, 2009
O estudo avaliou a atividade anti-helmíntica do extrato aquoso das folhas de Zanthoxylum rhoifolium em dois experimentos. O teste in vitro utilizou cultivos de fezes de caprinos tratados com diferentes concentrações do extrato: (134,5 a 335,0 mg.mL-1 ...
Peneluc Taíse, Domingues Luciana Ferreira, Gisele Nunes de Almeida, Maria Consuelo Caribé Ayres, Eduardo Luiz Trindade Moreira, Ana Carla Ferreira da Cruz, Thereza Cristina Bório dos Santos Calmon de Bittencourt, Maria Angela Ornelas de Almeida, Maria José Moreira Batatinha   +8 more
doaj   +1 more source

Plummer–Vinson syndrome in a 10‐year‐old boy from Côte d'Ivoire: An exceptional paediatric case with African context

JPGN Reports, EarlyView.
Abstract Plummer–Vinson syndrome (PVS) is characterised by the triad of dysphagia, iron‐deficiency anaemia, and proximal oesophageal webs. While well described in adults, paediatric cases remain exceptionally rare, particularly in sub‐Saharan Africa.
Paul Mike Tayou Mbobda, Hatrydt Guillaume Dimitri Kouamé, Amadou Ouattara   +2 more
wiley   +1 more source

Comprehensive Review on Medicinal Applications of Coumarin-Derived Imine–Metal Complexes

Molecules, 2022
Coumarins are fused six-membered oxygen-containing benzoheterocycles that join two synthetically useful rings: α-pyrone and benzene. A survey of the literature shows that coumarins and their metal complexes have received great interest from synthetic ...
Siddappa A. Patil, Vishal Kandathil, Anjali Sobha, Sasidhar B. Somappa, Max R. Feldman, Alejandro Bugarin, Shivaputra A. Patil   +6 more
doaj   +1 more source

Review of phytochemical and antioxidant properties of Ethiopian medicinal plants

JSFA reports, EarlyView.
Abstract Ethiopia possesses a rich ethnobotanical heritage and diverse medicinal flora that play an important role in traditional healthcare. Many Ethiopian medicinal plants contain bioactive phytochemicals with potential antioxidant properties. This capital of indigenous knowledge has contributed to the documentation of different medicinal plants that
Endalamaw Yihune, Amare Bitew Mekonnen, Getahun Yemata   +2 more
wiley   +1 more source

An Inventory of Anthelmintic Plants across the Globe

Pathogens, 2023
A wide range of novelties and significant developments in the field of veterinary science to treat helminth parasites by using natural plant products have been assessed in recent years.
Haroon Ahmed, Seyma Gunyakti Kilinc, Figen Celik, Harun Kaya Kesik, Sami Simsek, Khawaja Shafique Ahmad, Muhammad Sohail Afzal, Sumaira Farrakh, Waseem Safdar, Fahad Pervaiz, Sadia Liaqat, Jing Zhang, Jianping Cao   +12 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

First report of Ophiotaenia sp. in frogs (Amietophrynus kassasii) from Egypt and in vitro anticestodal activity of Sinularia sp. Extract [PDF]

Veterinary World
Background and Aim: Ophiotaenia species are globally distributed proteocephalidean cestodes that commonly parasitize amphibians and reptiles. Despite the ecological importance of frogs in controlling insect populations and maintaining food-web stability,
Barakat Shehata Abd Elmaleck, Mahmoud Abdelhamid, Abdallah Alian, Hind Alzaylaee, George D. Zouganelis, Gaber El-Saber Batiha, Marwa Adel Thabet, Fatma A. S. Anwar   +7 more
doaj   +1 more source

Moxidectin: A Viable Alternative for the Control of Ivermectin-Resistant Gastrointestinal Nematodes in Beef Cattle

Acta Veterinaria, 2022
The increasing prevalence of anthelmintic resistance in cattle especially for avermectins, is a challenge for controlling parasites in some herds. Thus, field studies demonstrating the increase in productivity by the use of anthelmintic formulations ...
Borges Dyego Gonçalves Lino, Conde Mário Henrique, Cunha Cibele Cristina Tavares, De Freitas Mariana Green, Moro Elio, De Almeida Borges Fernando   +5 more
doaj   +1 more source