Results 1 to 10 of about 129,084 (297)

A New Role for Old Friends: Effects of Helminth Infections on Vaccine Efficacy

Pathogens, 2022
Vaccines are one of the most successful medical inventions to enable the eradication or control of common and fatal diseases. Environmental exposure of hosts, including helminth infections, plays an important role in immune responses to vaccines.
Feifan Zhu, Wenyi Liu, Tong Liu, Linpeng Shi, Wenwen Zheng, Fei Guan, Jiahui Lei   +6 more
doaj   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Else KJ, Garcia FT, McSharry C, Nakajima H, Oku Y, Pawlowski Z, Petit‐Frere C, Robinson K, Tilney LG, Urban JF, WHO, WHO   +11 more
core   +4 more sources

Helminthic infections rates and malaria in HIV-infected pregnant women on anti-retroviral therapy in Rwanda. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Within sub-Saharan Africa, helminth and malaria infections cause considerable morbidity in HIV-positive pregnant women and their offspring. Helminth infections are also associated with a higher risk of mother-to-child HIV transmission.
Emil Ivan, Nigel J Crowther, Eugene Mutimura, Lawrence Obado Osuwat, Saskia Janssen, Martin P Grobusch   +5 more
doaj   +1 more source

School-Based Deworming Program Yields Small Improvement in Growth of Zanzibari School Children After one Year. [PDF]

, 1997
Efficacy trials of antihelminthic therapies conducted in Africa have reported improvements in children's growth, but nutritional evaluations of large-scale deworming programs are lacking.
Albonico, Albonico, Diggle, Ferguson, Hababu M. Chwaya, James M. Tielsch, Kruger, Latham, Lawless, Lorenzo Savioli, Marco Albonico, Must, Must, Rebecca J. Stoltzfus, Renganathan, Savioli, Savioli, Shiff, Stephenson, Stephenson, Stephenson, Stephenson, Stoltzfus, Stoltzfus, Warren, World Bank, World Health Organization, World Health Organization, World Health Organization, World Health Organization Expert Committee   +29 more
core   +1 more source

Spatial distribution of soil-transmitted helminths, including Strongyloides stercoralis, among children in Zanzibar

Geospatial Health, 2008
A programme periodically distributing anthelminthic drugs to school-aged children for the control of soiltransmitted helminthiasis was launched in Zanzibar in the early 1990s.
Stefanie Knopp, Khalfan A. Mohammed, I. Simba Khamis, Ali F. Mgeni, J. Russell Stothard, David Rollinson, Hanspeter Marti, Jürg Utzinger   +7 more
doaj   +1 more source

First study on the helminth community structure of the neotropical marsupial Metachirus myosuros (Didelphimorphia, Didelphidae)

Revista Brasileira de Parasitologia Veterinária, 2020
Metachirus myosuros is a marsupial species widely distributed in South America. Despite this, there is a lack of knowledge about its helminth parasites and helminth community structure.
Bruna Silva Cirino, Sócrates Fraga da Costa Neto, Arnaldo Maldonado Júnior, Rosana Gentile   +3 more
doaj   +1 more source

Diplomatic Assistance: Can Helminth-Modulated Macrophages Act as Treatment for Inflammatory Disease? [PDF]

PLoS Pathogens, 2016
Helminths have evolved numerous pathways to prevent their expulsion or elimination from the host to ensure long-term survival. During infection, they target numerous host cells, including macrophages, to induce an alternatively activated phenotype, which
Svenja Steinfelder, Noëlle Louise O'Regan, Susanne Hartmann   +2 more
doaj   +1 more source

Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

mBio, 2016
Immunoassays are currently needed to quantify Loa loa microfilariae (mf). To address this need, we have conducted proteomic and bioinformatic analyses of proteins present in the urine of a Loa mf-infected patient and used this information to identify ...
Papa M. Drame, Zhaojing Meng, Sasisekhar Bennuru, Jesica A. Herrick, Timothy D. Veenstra, Thomas B. Nutman   +5 more
doaj   +1 more source

Helminths in the hygiene hypothesis:Sooner or later? [PDF]

, 2014
There is increasing recognition that exposures to infectious agents evoke fundamental effects on the development and behaviour of the immune system. Moreover, where infections (especially parasitic infections) have declined, immune responses appear to be
Maizels, R. M., Mcsorley, H. J., Smyth, D. J.   +2 more
core   +4 more sources

Depression during Pregnancy in a Tertiary Care Center of Eastern Nepal

Journal of Nepal Medical Association, 2008
This is a cross sectional study, conducted in 45 pregnant women coming for antenatal check ups in the eastern regional hospitals in Nepal. Hamilton -Depression Scale (HAM-d) was applied after initial psychiatry work up to all women who were selected for ...
Rabi Shakya, S Sitaula, P M Shyangwa
doaj   +1 more source