Results 11 to 20 of about 58,691 (223)

Selective Packaging of miR-22 and miR-29 Orthologues into Extracellular Vesicles of the Porcine Whipworm Trichuris Suis. [PDF]

J Extracell Vesicles
ABSTRACT Helminths modulate host immunity, and in this respect, the porcine whipworm Trichuris suis has been explored clinically as an immunotherapy for inflammatory diseases. T. suis secretes a complex mixture of excretory/secretory products (ESP), including extracellular vesicles (EVs), nanosized membranous particles with bioactive cargoes of lipids,
Whitehead B, Mardahl M, Hansen EP, Fromm B, Borup A, Boysen AT, Atay JCL, Nørregaard R, Stensballe A, Andersen SD, Gasser RB, Brucale M, Valle F, Ridolfi A, Glud EN, Fredholm M, Williams AR, Thamsborg SM, Palmfedt J, Nejsum P.   +19 more
europepmc   +2 more sources

Necator americanus and helminth co-infections: further down-modulation of hookworm-specific type 1 immune responses. [PDF]

, 2011
BACKGROUND: Helminth co-infection in humans is common in tropical regions of the world where transmission of soil-transmitted helminths such as Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale as ...
Jeffrey Michael Bethony, Correa-Oliveira, Rodrigo, Geiger Stefan Michael, Brooker Simon, Brooker, Simon, Bonnie Cundill, Bethony Jeffrey Michael, Geiger, Stefan Michael, Cundill, Bonnie, Correa-Oliveira Rodrigo, Diemert David Joseph, Fujiwara, Ricardo Toshio, Cundill Bonnie, Neal Douglas Edward Alexander, David Joseph Diemert, Rodrigo Correa-Oliveira, Oliveira, Rodrigo Corrêa, Simon Brooker, Alexander Neal Douglas Edward, Alexander, Neal Douglas Edward, Bethony, Jeffrey Michael, Diemert, David Joseph, Fujiwara Ricardo Toshio, Stefan Michael Geiger, Ricardo Toshio Fujiwara   +24 more
core   +1 more source

Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People's Republic of China [PDF]

, 2013
Soil-transmitted helminth infections affect tens of millions of individuals in the People's Republic of China (P.R. China). There is a need for high-resolution estimates of at-risk areas and number of people infected to enhance spatial targeting of ...
Zhou, Xiao-Nong, Lai, Ying-Si, Utzinger, Jürg, Ying-Si Lai, Xiao-Nong Zhou, Vounatsou, Penelope, Jürg Utzinger, Penelope Vounatsou   +7 more
core   +1 more source

Human helminth therapy to treat inflammatory disorders - where do we stand? [PDF]

, 2015
Parasitic helminths have evolved together with the mammalian immune system over many millennia and as such they have become remarkably efficient modulators in order to promote their own survival.
Helmby, Helena, Helena Helmby
core   +1 more source

Modelling the geographical distribution of soil-transmitted helminth infections in Bolivia [PDF]

, 2013
The prevalence of infection with the three common soil-transmitted helminths (i.e. Ascaris lumbricoides, Trichuris trichiura, and hookworm) in Bolivia is among the highest in Latin America. However, the spatial distribution and burden of soil-transmitted
Utzinger, Jürg, Scholte, Ronaldo Gc, Chammartin, Frédérique, Bavia, Mara E., Vounatsou, Penelope, Malone, John B., Nieto, Prixia   +6 more
core   +1 more source

Helminth-induced prostaglandin signaling and dietary shifts in PUFA metabolism promote colitis-associated cancer [PDF]

Oxylipins derived from dietary polyunsaturated fatty acids (PUFAs) are key determinants of intestinal health, homeostasis, and inflammatory disorders, such as colitis-associated colorectal cancer. Previous research has independently linked a high dietary
William Horsnell (21066185), Matthew G Darby (22249795), Awen Gallimore (50379), Claire Butters (12490086), Katherine A Smith (22249786), Valerie B O’Donnell (14757400), Alisha Chetty (2273359), Ella K Reed (22249789), Irina Guschina (542401), Victoria J Tyrrell (22249792), Brunette Katsandegwaza (760689)   +10 more
core   +6 more sources

Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa. [PDF]

, 2012
BACKGROUND: Plasmodium-helminth coinfection can have a number of consequences for infected hosts, yet our knowledge of the epidemiology of coinfection across multiple settings is limited.
Pullan, Rachel L, Pullan, RL, Kolaczinski, JH, Kolaczinski, Jan H, Snow, RW, Brooker, Simon J, Ashton, Ruth A, Snow, Robert, Kabatereine, NB, Kabatereine, Narcis B, Gitonga, Caroline W, Brooker, SJ, Snow, Robert W, Ashton, RA, Gitonga, CW   +14 more
core   +1 more source

ICOS controls Foxp3+ regulatory T-cell expansion, maintenance, and IL-10 production during helminth infection [PDF]

, 2012
Foxp3+ regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity ...
van der Werf, Nienke, MacDonald, Andrew, Redpath, Stephen A, Taylor, Matthew, Cervera, Ana M, Macdonald, Andrew S; id_orcid, Cervera, Ana, Taylor, Matthew D., Maizels, Rick M, Andrew S. MacDonald, Cervera, Ana M., Gray, David, Maizels, Rick, Stephen A. Redpath, Maizels, Rick M., Taylor, Matthew D, Macdonald, Andrew S.; id_orcid, Redpath, Stephen A., Matthew D. Taylor, Rick M. Maizels, David Gray, Nienke van der Werf, Ana M. Cervera   +22 more
core   +1 more source

Helminth infection in southern Laos: high prevalence and low awareness [PDF]

, 2013
BACKGROUND: Helminthiasis is a public health concern in Lao People’s Democratic Republic (Lao PDR, Laos). This study aimed to understand helminth infection and associated risk factors in relation to existing local knowledge, attitudes and practices ...
Xayaseng, Vilavanh, Akkhavong, Kongsap, Vonghachack, Youthanavanh, van Eeuwijk, Peter, Phongluxa, Khampheng, Odermatt, Peter   +5 more
core   +1 more source

Suppression of allergic airway inflammation by helminth-induced regulatory T cells [PDF]

, 2005
Allergic diseases mediated by T helper type (Th) 2 cell immune responses are rising dramatically in most developed countries. Exaggerated Th2 cell reactivity could result, for example, from diminished exposure to Th1 cell–inducing microbial infections ...
Lamb, Jonathan, Mark S. Wilson, Adam Balic, Constance A.M. Finney, Taylor, Matthew D, Finney, Constance A, Matthew D. Taylor, Rick M. Maizels, Maizels, Rick, Jonathan R. Lamb, Wilson, Mark A, Balic, Adam   +11 more
core   +1 more source