Results 11 to 20 of about 60,573 (274)

Helminths and Immunological Tolerance [PDF]

Transplantation, 2014
Current immunosuppression regimens for solid-organ transplantation have shown disappointing efficacy in the prevention of chronic allograft rejection and carry unacceptable risks including toxicity, neoplasia, and life-threatening infection. Achievement of immunological tolerance (long-term antigen unresponsiveness in an immunocompetent host) presents ...
Johnston, Chris J.C., McSorley, Henry J., Anderton, Stephen M., Wigmore, Stephen J., Maizels, Rick M.   +4 more
openaire   +7 more sources

Editorial: Helminth biodiversity

Frontiers in Veterinary Science, 2023
The aim of this Research Topic is to broaden and deepen the knowledge about helminths in wildlife or domestic hosts around the world focusing on the contribution to the taxonomic groups, ecology, phylogenetic, and biology. Thus, a multidisciplinary approach is given and can be used as a guide for scientific information.
Simões, Raquel de O., Robles, María del Rosario   +1 more
openaire   +4 more sources

Necator americanus and helminth co-infections: further down-modulation of hookworm-specific type 1 immune responses. [PDF]

, 2011
BACKGROUND: Helminth co-infection in humans is common in tropical regions of the world where transmission of soil-transmitted helminths such as Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale as ...
Jeffrey Michael Bethony, Correa-Oliveira, Rodrigo, Geiger Stefan Michael, Brooker Simon, Brooker, Simon, Bonnie Cundill, Bethony Jeffrey Michael, Geiger, Stefan Michael, Cundill, Bonnie, Correa-Oliveira Rodrigo, Diemert David Joseph, Fujiwara, Ricardo Toshio, Cundill Bonnie, Neal Douglas Edward Alexander, David Joseph Diemert, Rodrigo Correa-Oliveira, Oliveira, Rodrigo Corrêa, Simon Brooker, Alexander Neal Douglas Edward, Alexander, Neal Douglas Edward, Bethony, Jeffrey Michael, Diemert, David Joseph, Fujiwara Ricardo Toshio, Stefan Michael Geiger, Ricardo Toshio Fujiwara   +24 more
core   +1 more source

Differential Effect of Ivermectin on Intestinal Helminths in Multimmate Mouse (Mastomys natalensis). [PDF]

Vet Med Sci
Mastomys natalensis harbours gastrointestinal helminths of public health and food‐safety importance. This study identified five helminth taxa and assessed faecal egg counts after a single ivermectin dose. Egg counts declined substantially in treated rodents but changed little in controls over eight weeks.
Thomas C, Msoffe V, Mwamengele G, Kessy S, Hape E, Katusi G, Sabuni C, Makundi I, Leirs H, Machang'u R.   +9 more
europepmc   +2 more sources

Human helminth therapy to treat inflammatory disorders - where do we stand? [PDF]

, 2015
Parasitic helminths have evolved together with the mammalian immune system over many millennia and as such they have become remarkably efficient modulators in order to promote their own survival.
Helmby, Helena, Helena Helmby
core   +1 more source

ICOS controls Foxp3+ regulatory T-cell expansion, maintenance, and IL-10 production during helminth infection [PDF]

, 2012
Foxp3+ regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity ...
van der Werf, Nienke, MacDonald, Andrew, Redpath, Stephen A, Taylor, Matthew, Cervera, Ana M, Macdonald, Andrew S; id_orcid, Cervera, Ana, Taylor, Matthew D., Maizels, Rick M, Andrew S. MacDonald, Cervera, Ana M., Gray, David, Maizels, Rick, Stephen A. Redpath, Maizels, Rick M., Taylor, Matthew D, Macdonald, Andrew S.; id_orcid, Redpath, Stephen A., Matthew D. Taylor, Rick M. Maizels, David Gray, Nienke van der Werf, Ana M. Cervera   +22 more
core   +1 more source

Modelling the geographical distribution of soil-transmitted helminth infections in Bolivia [PDF]

, 2013
The prevalence of infection with the three common soil-transmitted helminths (i.e. Ascaris lumbricoides, Trichuris trichiura, and hookworm) in Bolivia is among the highest in Latin America. However, the spatial distribution and burden of soil-transmitted
Utzinger, Jürg, Scholte, Ronaldo Gc, Chammartin, Frédérique, Bavia, Mara E., Vounatsou, Penelope, Malone, John B., Nieto, Prixia, Mara E Bavia, Malone JB, Ronaldo GC Scholte, Chammartin F, Frédérique Chammartin, Utzinger J, Nieto P, John B Malone, Penelope Vounatsou, Vounatsou P, Prixia Nieto, Bavia ME, Jürg Utzinger, Scholte RG   +20 more
core   +1 more source

Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa. [PDF]

, 2012
BACKGROUND: Plasmodium-helminth coinfection can have a number of consequences for infected hosts, yet our knowledge of the epidemiology of coinfection across multiple settings is limited.
Pullan, Rachel L, Kolaczinski, Jan H, Brooker, Simon J, Ashton, Ruth A, Kabatereine, Narcis B, Gitonga, Caroline W, Snow, Robert W   +6 more
core   +1 more source

Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth [PDF]

, 2012
Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of
Isabella M. Cattadori, Réka Albert (31571), Juilee Thakar (31567), Albert Réka, Ashutosh K Pathak, Lisa Murphy, Ashutosh K. Pathak, Albert, R., Ashutosh K. Pathak (188188), Cattadori Isabella M., Pathak, A.K., Thakar, J., Juilee Thakar, Murphy Lisa, Thakar Juilee, Cattadori, I.M., Lisa Murphy (188192), Réka Albert, Pathak Ashutosh K., Isabella M. Cattadori (130510), Isabella M Cattadori, Murphy, L.   +21 more
core   +2 more sources

Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People's Republic of China [PDF]

, 2013
Soil-transmitted helminth infections affect tens of millions of individuals in the People's Republic of China (P.R. China). There is a need for high-resolution estimates of at-risk areas and number of people infected to enhance spatial targeting of ...
Zhou, Xiao-Nong, Lai, Ying-Si, Utzinger, Jürg, Ying-Si Lai, Xiao-Nong Zhou, Vounatsou, Penelope, Jürg Utzinger, Penelope Vounatsou, Lai YS, Zhou XN, Utzinger J, Vounatsou P   +11 more
core   +1 more source