Results 31 to 40 of about 35,870 (226)

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Binding and cleavage of pro-urokinase by a tegument extract of Fasciola hepatica newly excysted juveniles activate the host fibrinolytic system

Veterinary Research
Plasmin, the final product of fibrinolysis, is a broad-spectrum serine protease that degrades extracellular matrix (ECM) components, a function exploited by multiple pathogens for dissemination purposes.
Judit Serrat, María Torres-Valle, Carolina De Marco Verissimo, Mar Siles-Lucas, Javier González-Miguel   +4 more
doaj   +1 more source

Dynamics of Interleukin-9 Producing Lymphocytes in Strongyloides ratti-Infected Mice

Pathogens
Helminths infect a quarter of the human population and are controlled in the frame of a canonical type-2 immune response. Interleukin-9 is a cytokine with pleiotropic functions during type-2 immunity that can be produced by many different cells ...
Wiebke Hartmann, Lennart Heepmann, Lara Linnemann, Paula Licona-Limon, Florent Colomb, Tania Frangova, Henry J. McSorley, Minka Breloer   +7 more
doaj   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis)

The Anatomical Record, EarlyView.
Abstract Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century. Several factors have been proposed to underlie this replacement, but here we investigated the potential for dietary competition in which gray squirrels have better feeding performance than ...
Philip G. Cox, Peter J. Watson
wiley   +1 more source

Fibrinolysis-unrelated functions of the plasminogen/plasmin system: A gateway to successful parasitism?

Current Research in Parasitology and Vector-Borne Diseases
Parasites have evolved remarkable mechanisms to exploit host resources by subverting key physiological pathways to facilitate their survival and transmission.
Judit Serrat, Mar Siles-Lucas, Javier González-Miguel   +2 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Helminth fauna of the monocled cobra (Naja kaouthia) from central Thailand: community composition and taxonomic perspectives

Parasitology
Snakes serve as important hosts for parasites at the interface of wildlife, humans and domestic animals. However, their helminth fauna in tropical regions, particularly Thailand, remains poorly documented.
Napat Ratnarathorn, Urusa Thaenkham, Abigail Hui En Chan, Panithi Laoungbua, Tanapong Tawan, Taksa Vasaruchapong, Vachirapong Charoennitiwat, Kittipong Chaisiri   +7 more
doaj   +1 more source

The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis.

PLoS Neglected Tropical Diseases, 2019
BackgroundIndividual helminth infections are ubiquitous in the tropics; geographical overlaps in endemicity and epidemiological reports suggest areas endemic for multiple helminthiases are also burdened with high prevalences of intestinal protozoan ...
Rose E Donohue, Zoë K Cross, Edwin Michael   +2 more
doaj   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source