Results 51 to 60 of about 35,870 (226)

Guidelines for the purification and characterization of extracellular vesicles of parasites

Journal of Extracellular Biology, 2023
Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs)
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia deAlmeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas   +30 more
doaj   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Effects of helminths and anthelmintic treatment on cardiometabolic diseases and risk factors: A systematic review

PLoS Neglected Tropical Diseases, 2023
Background Globally, helminth infections and cardiometabolic diseases often overlap in populations and individuals. Neither the causal relationship between helminth infections and cardiometabolic diseases nor the effect of helminth eradication on ...
Khanh Pham, Anna Mertelsmann, Keith Mages, Justin R. Kingery, Humphrey D. Mazigo, Hyasinta Jaka, Fredrick Kalokola, John M. Changalucha, Saidi Kapiga, Robert N. Peck, Jennifer A. Downs   +10 more
doaj  

Benzimidazole Anthelmintic Compounds Albendazole and Fenbendazole Show Distinct Toxicity on the Nitrogen Fixing Bacterium Mesorhizobium loti and Its Symbiosis With Lotus japonicus

Environmental Toxicology, EarlyView.
ABSTRACT Veterinary medicines, which reach the soil mostly through the application of contaminated manures, can affect beneficial soil microorganisms, such as nitrogen‐fixing rhizobia bacteria, which engage in important symbiotic associations with plants.
Polyxeni Gorgia, Stathis Lagos, Christina N. Nikolaou, Nikoleta Basdeki, Christos Papadopoulos, Dimitrios G. Karpouzas, Daniela Tsikou   +6 more
wiley   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source

Taxon, Arboreality, Sex, and Season—Factors Influencing Gastrointestinal Parasite Occurrence in Zoo‐Housed Non‐Human Primates

Zoo Biology, EarlyView.
ABSTRACT The emergence of anthelminthic resistance is a well‐documented phenomenon in livestock and companion animals. Given the scarcity of new antiparasitic drugs, the implementation of effective, holistic anthelminthic control strategies is critical to preserving the efficacy of existing treatments.
Stalder Sandro, Hatt Jean‐Michel
wiley   +1 more source

Integrating infection intensity and aggregation into the dynamics of pathogens with within‐host replication

Journal of Animal Ecology, EarlyView.
We bridge micro‐ and macroparasite theory with a model tracking pathogen load heterogeneity. By incorporating load‐dependent mortality and within‐host pathogen growth, we show how pathogen load aggregation alters disease prevalence, host suppression effects, and virulence evolution, providing insights for managing complex infectious disease like ...
Ruijiao Sun, Jason Cosens Walsman, Mark Wilber, Cheryl J. Briggs   +3 more
wiley   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

Integrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source

CD4 T Cells in Mycobacterium tuberculosis and Schistosoma mansoni Co-infected Individuals Maintain Functional TH1 Responses

Frontiers in Immunology, 2020
Mycobacterium tuberculosis (Mtb) is a serious public health concern, infecting a quarter of the world and leading to 10 million cases of tuberculosis (TB) disease and 1. 5 million deaths annually.
Taryn A. McLaughlin, Jeremiah Khayumbi, Joshua Ongalo, Joan Tonui, Angela Campbell, Salim Allana, Samuel Gurrion Ouma, Felix Hayara Odhiambo, Neel R. Gandhi, Neel R. Gandhi, Cheryl L. Day, Cheryl L. Day   +11 more
doaj   +1 more source

Drivers of Mouse Plagues: Exceptional Rainfall Following Prolonged Drought Triggers Mouse Plagues in Southeastern Australia

Integrative Zoology, EarlyView.
This study identified a specific sequence of an extended drought followed by exceptional rainfall as a necessary precursor for mouse plagues in southeastern Australia. Long‐term rainfall anomalies interact with ecological processes to reset population dynamics, creating conditions that support rapid mouse population growth following periods of ...
Peter R. Brown
wiley   +1 more source