The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes [PDF]
Nematodes represent one of the most abundant and species-rich groups of animals on the planet, with parasitic species causing chronic, debilitating infections in both livestock and humans worldwide. The prevalence and success of the nematodes is a direct
ANDREW J. BIRNIE +5 more
core +1 more source
Melanoma: Pathogenesis and Targeted Therapy
The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu +5 more
wiley +1 more source
Modelling the impacts of pasture contamination and stocking rate for the development of targeted selective treatment strategies for Ostertagia ostertagi infection in calves [PDF]
A simulation study was carried out to assess whether variation in pasture contamination or stocking rate impact upon the optimal design of targeted selective treatment (TST) strategies. Two methods of TST implementation were considered: 1) treatment of a
Berk, Zoe +3 more
core +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Effects of condensed tannins on goats experimentally infected with Haemonchus contortus. [PDF]
Although the use of tanniferous plants or condensed tannins as an alternative to anthelmintics to control gastrointestinal nematodes has been largely documented in sheep, studies remain scarce in goats.
C., GRISEZ +5 more
core +1 more source
Anthelmintics V: Drugs, resistance, and vaccines [PDF]
Raffi V. Aroian +2 more
openalex +1 more source
Resistance to anthelmintics in gastrointestinal nematodes (GINs) is highly prevalent, as these parasites have been treated with anthelmintics for decades in ruminants and horses.
Jacques Cabaret
doaj +1 more source
First Report of Anthelmintic Resistance in Gastrointestinal Nematodes of Sheep from Costa Rica
As the prevalence and severity of anthelmintic resistance continue to rise, nematode infections in sheep correspondingly reduce the profitability of the sheep industry. In Costa Rica, sheep production systems are increasing in both number and importance.
R. Maroto +5 more
doaj +1 more source
Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat [PDF]
An understanding of how genes move between and within populations of parasitic nematodes is important in combating the evolution and spread of anthelmintic resistance.
Adam, A. +5 more
core +1 more source
Resistance of strongylid nematodes to anthelmintic drugs and driving factors at Czech goat farms [PDF]
Jaroslav Vadlejch +3 more
openalex +2 more sources

