Results 1 to 10 of about 29,812 (195)

Chalcone and Trans-Chalcone Induce Transcriptomic Changes in Caenorhabditis elegans Compatible with a Novel Cumulative Damage Mode of Action [PDF]

Molecules
Chalcones, a subclass of flavonoid-derived phenolic compounds, have demonstrated promising anthelmintic activity against parasitic nematodes. This study aimed to obtain insights into the biological effects a cis/trans mixture of chalcone and its ...
Giulio Galli, Carl S. Bruun, Carlos García-Estrada, Rafael Balaña-Fouce, María Martinez-Valladares, Tina V. A. Hansen   +5 more
doaj   +2 more sources

Cost-benefit ratio of anthelmintic treatment and its comparative efficacy in commercial dairy farms

Frontiers in Veterinary Science, 2022
Intestinal parasitic infection is one of the major challenges in obtaining optimal production and maintaining the health and welfare of all animals including cattle and buffaloes. Anti-parasitic treatments appear to be a reliable countermeasure. However,
Muhammad Rashid, Naveed Zahra, Amna Chudhary, Tauseef Ur Rehman, Muhammad Tahir Aleem, Abdulaziz Alouffi, Aymen Mohammed, Muhammad Imran Rashid, Muhammad Ehsan, Muhammad Irfan Malik, Ghulam Hussain Dilber, Amir Bakhsh, Mashal M. Almutairi   +12 more
doaj   +1 more source

High Throughput Screening of the NatureBank ‘Marine Collection’ in a Haemonchus Bioassay Identifies Anthelmintic Activity in Extracts from a Range of Sponges from Australian Waters

Molecules, 2021
Widespread resistance in parasitic nematodes to most classes of anthelmintic drugs demands the discovery and development of novel compounds with distinct mechanisms of action to complement strategic or integrated parasite control programs.
Aya C. Taki, Joseph J. Byrne, Abdul Jabbar, Kah Yean Lum, Sasha Hayes, Russell S. Addison, Kelsey S. Ramage, Andreas Hofmann, Merrick G. Ekins, Tao Wang, Bill C. H. Chang, Rohan A. Davis, Robin B. Gasser   +12 more
doaj   +1 more source

The Use of Molecular Profiling to Track Equine Reinfection Rates of Cyathostomin Species Following Anthelmintic Administration

Animals, 2021
Cyathostomins are a multispecies parasite ubiquitous in Equids. Cyathostomins have developed resistance to all but one class of anthelmintics, but species-level sensitivity to anthelmintics has not been shown.
Alexa C. B. Johnson, Amy S. Biddle
doaj   +1 more source

Microfluidic-Based Formulation of Essential Oils-Loaded Chitosan Coated PLGA Particles Enhances Their Bioavailability and Nematocidal Activity

Pharmaceutics, 2022
In this study, poly (lactic-co-glycolic) acid (PLGA) particles were synthesized and coated with chitosan. Three essential oil (EO) components (eugenol, linalool, and geraniol) were entrapped inside these PLGA particles by using the continuous flow ...
Mohamed A. Helal, Ahmed M. Abdel-Gawad, Omnia M. Kandil, Marwa M. E. Khalifa, Alison A. Morrison, David J. Bartley, Gareth W. V. Cave, Hany M. Elsheikha   +7 more
doaj   +1 more source

Assessment of the chemical and genetic variability among accessions of Cicerbita alpina (L.) Wallr., an alpine plant with anthelmintic properties

Frontiers in Plant Science, 2023
Cicerbita alpina (L.) Wallr, is a perennial alpine plant and a member of the Asteraceae family, typically found at altitudes above 1000 meters in the Italian Alps.
Eftychia Martinidou, Luisa Palmieri, Maddalena Sordo, Domenico Masuero, Maria Ourda, Luca Delucchi, Pietro Fusani, Veronika Tremml, Ioanna Poulopoulou, Matthias Gauly, Mark J. Horgan, Bianka Siewert, Hermann Stuppner, Stefan Martens   +13 more
doaj   +1 more source

Xenobiotic-Metabolizing Enzymes in Trematodes

Biomedicines, 2022
Trematode infections occur worldwide causing considerable deterioration of human health and placing a substantial financial burden on the livestock industry. The hundreds of millions of people afflicted with trematode infections rely entirely on only two
Viatcheslav Mordvinov, Maria Pakharukova
doaj   +1 more source

Development of In Vitro Assays with the Canine Hookworm Uncinaria stenocephala and Assessment of Natural Plant Products for Anti-Parasitic Activity

Pathogens, 2023
Enteric helminth infection is an increasing concern in companion animals due to reports of resistance to commonly used anthelmintic drugs. Thus, the assessment of new therapeutic options such as bioactive dietary additives is of high importance. Here, we
Heidi A. Geisshirt, Charlotte S. Bonde, Caroline Marcussen, Helena Mejer, Andrew R. Williams   +4 more
doaj   +1 more source

Impact of Seasonal and Organ-Related Fluctuations on the Anthelmintic Properties and Chemical Profile of Cladium mariscus (L.) Pohl Extracts

Frontiers in Plant Science, 2022
The use of plants and their metabolites stands as a promising option to tackle parasitic infections by gastrointestinal nematodes (GIN) in integrated control strategies.
Marta Oliveira, Caroline Sprengel Lima, Eulogio J. Llorent-Martínez, Hervé Hoste, Hervé Hoste, Luísa Custódio   +5 more
doaj   +1 more source

Efektifitas Anthelmintika Ekstrak Etanol Kulit Buah Delima (Punica granatum) terhadap Jumlah Kematian Cacing Ascaridia gallisecara inVitro

Journal of Parasite Science, 2020
This research was conducted to determine the anthelmintics effect of peel a pomegranate fruit extract etanol against Ascaridia galli worm in vitro. In this research, using 240 samples of A. galli with length 7-11cm without differentiating sex.
Nila Murodah, Sri Mumpuni Sosiawati, Iwan Sahrial Hamid, Setiawan Koesdarto, Rochmah Kurniasanti, Poedji Hastutiek   +5 more
doaj   +1 more source