Results 101 to 110 of about 14,552 (200)

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Contribution to the study of anthelmintic resistance of sheep gastro-intestinal strongyles on a sheep farm in the Guelma region, north-east Algeria

Helminthologia
The prolonged use of anthelmintics is sometimes accompanied by a gradual decline in their effectiveness, refl ecting the development of resistant parasite strains. This study was conducted in the region of Guelma (northeastern Algeria) at the end of July
Djemai S., Zeghilet N., Boultif L., Ayadi O., Djafar Z.R.   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, Volume 600, Issue 17, Page 2547-2563, September 2026.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Environmental risks of anthelmintics

, 2019
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Nikoleta Dojčanská Supervisor: prof. Ing. Barbora Szotáková, Ph.D Title of diploma thesis: Environmental risks of anthelmintics Anthelmintics are drugs
Dojčanská, Nikoleta
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GC–MS‐Based Phytochemical Profiling and Integrated Evaluation of Antioxidant, Antibacterial, and In Silico Studies of Kumaun Himalayan Strobilanthes Species

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Himalayan Strobilanthes species: phytochemical profiling, bioactivities, and In silico Studies. ABSTRACT Five Strobilanthes species indigenous to the Kumaun Himalayan region of Uttarakhand, India, have been historically employed in traditional medicine to treat bacterial infections, inflammatory conditions, and respiratory ailments, but remain largely ...
Sakshi Negi, Ravendra Kumar, Vaishnavi Rawat, Pooja Bargali, Aashish Kumar Sagar, Stefania Garzoli, Riddhiman Lahiri, Shilpi Rawat, Avdhesh Kumar, Manmohan Singh Rawat, Jolanta Maslowiecka, Valery A. Isidorov, Dharmendra S. Rawat   +12 more
wiley   +1 more source

Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitro [PDF]

, 1993
Previous studies in our laboratory have shown that albendazole is effective against Giardia spp. in vitro and in vivo, prompting an investigation of the effects of several related benzimidazoles (BZs) on the viability of this protozoan parasite.
Thompson, R.C.A., Morgan, U.M., Reynoldson, J.A.   +2 more
core  

Anthelmintic Potential of Discarded Litchi chinensis Seeds: a sustainable approach to agricultural by-product utilization

Journal of Pharmacopuncture
Objectives: Litchi chinensis (Sonn.), belonging to the Sapindaceae family, has historically been used for the treatment of gastrointestinal ailments, including ulcers, gastritis, diarrhea, and infections.
Mustakin Ahmed Shohel, Md. Humayan Kabir, Sumaiya Siddika, Sheikh Arafat Rahman, Nirmal Chandra Mahat, Tarique Muhammad Tawabul Islam, Md. Rakibul Hasan Rahat, Ivvala AnShaker, Md. Abul Kashem Tang   +8 more
doaj   +1 more source

Computational, In Vitro, and In Vivo Evaluation of Benzimidazole–Pyrazole Hybrid Scaffolds as Multi‐Target Anti‐Ulcer Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The hybrid pharmacophore approach involves the combination of benzimidazole‐pyrazole moieties to form multi‐functional anti‐ulcer compounds. Molecular modeling and biological evaluations show significant proton pump inhibition, anti‐inflammatory action, antioxidant property, and remarkable prevention of gastric ulcers.
Hafiz Aamir Ali Kharl, Abdul Malik, Humaira Nadeem, Mohammad Shamsul Ola, Sara Aiman, Arif Ullah Khan, Muhammad Akmal Farooq, Humaira Muzaffar, Syed Muzzammil Masaud   +8 more
wiley   +1 more source

Effect of anthelmintics on expression of selected plant enzymes [PDF]

, 2018
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Bc. Martina Navrátilová Supervisor: Ing. Petra Matoušková, Ph.D.
Navrátilová, Martina
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MODERN STRATEGY, NEW METHODS AND MEANS FOR CONTROL OF HELMINTHIASES IN UZBEKISTAN

Ukrainian Journal of Veterinary Sciences, 2021
The modern strategy to control the main, widespread helminthiases of farm animals provides for a complex of anthelmintic measures, including planned therapeutic and preventive deworming based on data from the study of the epizootology of helminthiases in
A. O. ORIPOV, N. E. YULDASHEV
doaj