Results 81 to 90 of about 8,916 (194)

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig, Aya C. Taki, Joseph J. Byrne, Pierre Mesdom, Olivier Blacque, Cécile Häberli, Trix Zumkehr, Gonzalo Scalese, Leticia Pérez‐Díaz, Dinorah Gambino, Britta Lundström‐Stadelmann, Jennifer Keiser, Robin B. Gasser, Kevin Cariou, Gilles Gasser   +14 more
wiley   +1 more source

Evaluation of resistance in a selected field strain of Haemonchus contortus to ivermectin and moxidectin using the Larval Migration on Agar Test Avaliação da resistência em um isolado de campo selecionado de Haemonchus contortus à ivermectina e moxidectina usando o Teste de Migração de Larvas em Ágar

Pesquisa Veterinária Brasileira, 2013
Haemonchus contortus is one of the most common and economically significant causes of disease in small ruminants worldwide, and the control programs of parasitic nematodes - including H. contortus - rely mostly on the use of anthelmintic drugs.
Fernanda S. Fortes, Fernando S. Kloster, Andressa S. Schafer, Daniele Bier, Andréia Buzatti, Ursula Y. Yoshitani, Marcelo B. Molento   +6 more
doaj  

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2937-2948, August 2026.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

COMPARATIVE EFFICACY OF OXYCLOZANIDE, RAFOXANIDE AND BITHIONOL SULPHOXIDE AGAINST PARAMPHISTOMIASIS IN BUFFALOES

Pakistan Veterinary Journal, 2003
In this study comparative anthelmintic trials were conducted using Nilzan drench (Oxyclozanide 3.0% + Levamisole 1.5%), Fasifree (Rafoxanide 3.0%), Irchasol (Bithionol sulphoxide 10% + Levamisole 1.5%) and Nilvenn drench (Levamisole 1.5%) administered ...
M. Umar. M. Ashraf, K. Pervaiz and H. A. Hashmi
doaj  

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Age at First Reproduction Predicts Sex‐Specific Parasite Infection Trajectories Through Adulthood

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Age at first reproduction predicted sex‐specific infection trajectories in male but not female shags. Early‐ and modal‐recruiting males showed within‐individual declines in parasite burden with age, whereas late‐recruiting males exhibited progressive increases.
Francisco Ruiz‐Raya, Sarah J. Burthe, Hannah Ravenswater, Fiona Greco, Olivia Hicks, Mark Newell, Carrie Gunn, Francis Daunt, Emma J. A. Cunningham   +8 more
wiley   +1 more source

Chemical Profiles, Pharmacological Insights, and In Silico Studies of Antidesma montanum Blume: An Experimental and Computer‐Aided Approach

eFood, Volume 7, Issue 4, August 2026.
Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu, Najmul Alam, Sadia Farid Jhuma, Mohammad Nazmul Islam, Shady A. Alghazali, Md Abdul Awal, Sanjida Islam, Hafsa Siddiqua, Shafinaz Nur, Md. Sohel Rana   +9 more
wiley   +1 more source

Anthelmintic Potential of Discarded Litchi chinensis Seeds: a sustainable approach to agricultural by-product utilization

Journal of Pharmacopuncture
Objectives: Litchi chinensis (Sonn.), belonging to the Sapindaceae family, has historically been used for the treatment of gastrointestinal ailments, including ulcers, gastritis, diarrhea, and infections.
Mustakin Ahmed Shohel, Md. Humayan Kabir, Sumaiya Siddika, Sheikh Arafat Rahman, Nirmal Chandra Mahat, Tarique Muhammad Tawabul Islam, Md. Rakibul Hasan Rahat, Ivvala AnShaker, Md. Abul Kashem Tang   +8 more
doaj   +1 more source

MODERN STRATEGY, NEW METHODS AND MEANS FOR CONTROL OF HELMINTHIASES IN UZBEKISTAN

Ukrainian Journal of Veterinary Sciences, 2021
The modern strategy to control the main, widespread helminthiases of farm animals provides for a complex of anthelmintic measures, including planned therapeutic and preventive deworming based on data from the study of the epizootology of helminthiases in
A. O. ORIPOV, N. E. YULDASHEV
doaj  

Corticosterone Under Experimental Manipulation of Nutrition and Parasite Burden in a Wild Rodent System

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 749-758, August 2026.
ABSTRACT Environmental pressures shape survival and life‐history dynamics partly by triggering the release of glucocorticoids, whose short‐term benefits but long‐term costs make it essential to understand what drives their levels. Here, we used an experimental manipulation of two environmental stressors—food availability and parasite burden—to directly
Sarah E. Wolf, Olga Dłużniewska, Simon A. Babayan, Amy B. Pedersen, Tom J. Little   +4 more
wiley   +1 more source