Results 41 to 50 of about 14,552 (200)

Synthesis, characterization and anthelmintic activity evaluation of pyrimidine derivatives bearing carboxamide and sulphonamide moieties [PDF]

Journal of the Serbian Chemical Society, 2018
Pyrimidines, sulphonamides and carboxamides have shown a large number of pharmacological properties against different types of diseases including helminthiasis.
Ugwu David I., Okoro Uchechukwu C., Mishra Narendra K.   +2 more
doaj   +1 more source

Analysis of the range of drugs registered in the Russian Federation to control parasitic infections in pigs

Российский паразитологический журнал, 2023
The purpose of the research is the analysis of the range of antiparasitic drugs for pig breeding as registered in the Russian Federation and included in the State Register of Medicinal Products for Veterinary Use.The control of parasitic diseases is an ...
T. V. Gerunov, V. I. Dorozhkin, L. K. Gerunova, M. N. Gonochova, Ya. O. Kryuchek, A. A. Tarasenko, E. A. Chigrinski   +6 more
doaj   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

RESISTANCE TO ANTHELMINTICS

Trakia Journal of Sciences
In pasture-raised animals, parasitic infections result in significant financial losses. On the other hand, their prevention and limitation require significant financial resources.
V. Radev
doaj   +1 more source

Comparison of the in vitro anthelmintic effects of Acacia nilotica and Acacia raddiana

Parasite, 2017
Gastrointestinal nematodes are a major threat to small ruminant rearing in the Sahel area, where farmers traditionally use bioactive plants to control these worms, including Acacia nilotica and Acacia raddiana.
Zabré Geneviève, Kaboré Adama, Bayala Balé, Katiki Luciana M., Costa-Júnior Lívio Martins, Tamboura Hamidou H., Belem Adrien M.G., Abdalla Adibe L., Niderkorn Vincent, Hoste Hervé, Louvandini Helder   +10 more
doaj   +1 more source

Experience of eradicating parasites of laboratory rats in conventional vivarium

Российский паразитологический журнал, 2023
The purpose of the research is to test different dehelminthization schemes of laboratory rats infected with cestodes Rodentolepis nana and nematodes Syphacia muris and evaluate the significance of combined environment disinfection measures. The practical
D. N. Polukhina, O. A. Panova, O. P. Kurnosova, N. B. Emelyanova, N. Yu. Sysoeva, A. V. Khrustalev, L. I. Kachurina   +6 more
doaj   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections [PDF]

, 2016
Treatment options for infections with soil-transmitted helminths (STH) - Ascaris lumbricoides, Trichuris trichiura and the two hookworm species, Ancylostoma duodenale and Necator americanus - are limited despite their considerable global health burden ...
Ivan Scandale (349072), Jennifer Keiser, Mireille Vargas (392661), Ivan Scandale, Noemi Cowan, Adelfio, Roberto, Panic, Gordana, Gordana Panic, Roberto Adelfio, Cowan, Noemi, Gordana Panic (507685), Roberto Adelfio (392660), Keiser, Jennifer, Scandale, Ivan, Jennifer Keiser (39606), Vargas, Mireille, Noemi Cowan (507684), Mireille Vargas   +17 more
core   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Plummer–Vinson syndrome in a 10‐year‐old boy from Côte d'Ivoire: An exceptional paediatric case with African context

JPGN Reports, EarlyView.
Abstract Plummer–Vinson syndrome (PVS) is characterised by the triad of dysphagia, iron‐deficiency anaemia, and proximal oesophageal webs. While well described in adults, paediatric cases remain exceptionally rare, particularly in sub‐Saharan Africa.
Paul Mike Tayou Mbobda, Hatrydt Guillaume Dimitri Kouamé, Amadou Ouattara   +2 more
wiley   +1 more source