Results 31 to 40 of about 14,552 (200)
Molecules, 2021 Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthelmintics with distinct mechanisms of action.
Aya C. Taki +11 more
doaj +1 more source
Anthelmintics Effects on Worms
, 2022 Body curls in actively moving C. elegans upon exposure to anthelmintics. (a) Snapshots of a representative worm (every 500 ms) as it curls its body such that the head touches or overlaps its tail.
Santosh Pandey (12981308)
core +1 more source
Pathogens, 2022 While there have been legitimate concerns in the past regarding the use of anthelmintics for the management of neuroangiostrongyliasis (rat lungworm disease), recent studies demonstrate that they can be considered safe and efficacious, particularly ...
John Jacob +3 more
doaj +1 more source
UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus
Frontiers in Physiology, 2020 The nematode Haemonchus contortus, a gastrointestinal parasite of ruminants, can severely burden livestock production. Although anthelmintics are the mainstay in the treatment of haemonchosis, their efficacy diminishes due to drug-resistance development ...
Pavlína Kellerová +7 more
doaj +1 more source
Pharmacological receptors of nematoda as target points for action of antiparasitic drugs [PDF]
Veterinarski Glasnik, 2010 Cholinergic receptors of parasitic nematodes are one of the most important possible sites of action of antiparasitic drugs. This paper presents some of our own results of electrophysiological and pharamcological examinations of nicotinic and muscarinic ...
Trailović Saša M. +3 more
doaj +1 more source
Veterinary Research, 2020 The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g.
Pavlína Kellerová +8 more
doaj +1 more source
Antiparasitic Tannin-Rich Plants from the South of Europe for Grazing Livestock: A Review
Animals, 2023 Internal parasites are one of the main causes of health threats in livestock production, especially in extensive livestock farming. Despite the environmental toxic effects (loss of dung beetles, biodiversity, and other issues) and resistance phenomenon ...
Pablo Rodríguez-Hernández +7 more
doaj +1 more source
Neurocysticercosis: Current Perspectives on Diagnosis and Management
Frontiers in Veterinary Science, 2021 Porcine cysticercosis, human taeniasis, and (neuro)cysticercosis are endemic in many low- and middle-income countries (LMIC) where they present a significant health burden to affected communities.
Caitlin Butala +6 more
doaj +1 more source
Advanced Science, EarlyView.Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang +5 more
wiley +1 more source
Animal Research and One Health, EarlyView.Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source