Results 31 to 40 of about 8,916 (194)
UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus
Frontiers in Physiology, 2020 The nematode Haemonchus contortus, a gastrointestinal parasite of ruminants, can severely burden livestock production. Although anthelmintics are the mainstay in the treatment of haemonchosis, their efficacy diminishes due to drug-resistance development ...
Pavlína Kellerová +7 more
doaj +1 more source
Pharmacological receptors of nematoda as target points for action of antiparasitic drugs [PDF]
Veterinarski Glasnik, 2010 Cholinergic receptors of parasitic nematodes are one of the most important possible sites of action of antiparasitic drugs. This paper presents some of our own results of electrophysiological and pharamcological examinations of nicotinic and muscarinic ...
Trailović Saša M. +3 more
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Veterinary Research, 2020 The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g.
Pavlína Kellerová +8 more
doaj +1 more source
Antiparasitic Tannin-Rich Plants from the South of Europe for Grazing Livestock: A Review
Animals, 2023 Internal parasites are one of the main causes of health threats in livestock production, especially in extensive livestock farming. Despite the environmental toxic effects (loss of dung beetles, biodiversity, and other issues) and resistance phenomenon ...
Pablo Rodríguez-Hernández +7 more
doaj +1 more source
Neurocysticercosis: Current Perspectives on Diagnosis and Management
Frontiers in Veterinary Science, 2021 Porcine cysticercosis, human taeniasis, and (neuro)cysticercosis are endemic in many low- and middle-income countries (LMIC) where they present a significant health burden to affected communities.
Caitlin Butala +6 more
doaj +1 more source
Advanced Science, EarlyView.Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang +5 more
wiley +1 more source
Synthesis, characterization and anthelmintic activity evaluation of pyrimidine derivatives bearing carboxamide and sulphonamide moieties [PDF]
Journal of the Serbian Chemical Society, 2018 Pyrimidines, sulphonamides and carboxamides have shown a large number of pharmacological properties against different types of diseases including helminthiasis.
Ugwu David I. +2 more
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Animal Research and One Health, EarlyView.Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source
Comparison of the in vitro anthelmintic effects of Acacia nilotica and Acacia raddiana
Parasite, 2017 Gastrointestinal nematodes are a major threat to small ruminant rearing in the Sahel area, where farmers traditionally use bioactive plants to control these worms, including Acacia nilotica and Acacia raddiana.
Zabré Geneviève +10 more
doaj +1 more source