Results 11 to 20 of about 46,307 (274)

Application of Mesoporous Silica Nanoparticles in Cancer Therapy and Delivery of Repurposed Anthelmintics for Cancer Therapy

Pharmaceutics, 2022
This review focuses on the biomedical application of mesoporous silica nanoparticles (MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and specifically on overcoming the challenges of currently available anthelmintics (e.
Maedeh Koohi Moftakhari Esfahani, S. Alavi, P. Cabot, N. Islam, E. Izake   +4 more
semanticscholar   +1 more source

PHYTOCHEMICALS AS ALTERNATIVE ANTHELMINTICS AGAINST POULTRY PARASITES: A REVIEW

Agrobiological Records, 2023
Parasitic diseases causing considerable losses are one of the most common infections in humans, animals, and birds. This review emphasizes the devastation of the poultry industry by parasites and the use of bioactive components of plants as an ...
Shahid Ahmad
semanticscholar   +1 more source

World association for the advancement of veterinary parasitology (WAAVP) guideline for the evaluation of the efficacy of anthelmintics in food-producing and companion animals: general guidelines.

Veterinary parasitology, 2022
The general WAAVP (World Association for the Advancement of Veterinary Parasitology) guideline on anthelmintic efficacy were prepared to assist researchers with the planning, conduct and interpretation of studies to assess the efficacy of anthelmintic ...
T. Geurden, Emil R. Smith, J. Vercruysse, T. Yazwinski, T. Settje, M. K. Nielsen   +5 more
semanticscholar   +1 more source

In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity

ACS Omega, 2021
Cancer is a leading cause of death worldwide and its incidence is unfortunately anticipated to rise in the next years. On the other hand, vascular endothelial growth factor receptor 2 (VEGFR-2) is highly expressed in tumor-associated endothelial cells ...
Ayman Abo Elmaaty, K. Darwish, A. Chrouda, Amira A. Boseila, M. Tantawy, Sameh S. Elhady, A. Shaik, Muhamad Mustafa, A. Al-karmalawy   +8 more
semanticscholar   +1 more source

Egg reappearance periods of anthelmintics against equine cyathostomins: The state of play revisited.

International Journal for Parasitology: Drugs and Drug Resistance, 2022
Cyathostomins are the most common and highly prevalent parasites of horses worldwide. Historically, the control of cyathostomins has mainly relied on the routine use of anthelmintic products.
Steph Macdonald, G. Abbas, A. Ghafar, C. Gauci, J. Bauquier, C. El-Hage, B. Tennent-Brown, E. Wilkes, A. Beasley, C. Jacobson, L. Cudmore, P. Carrigan, J. Hurley, I. Beveridge, K. Hughes, M. K. Nielsen, A. Jabbar   +16 more
semanticscholar   +1 more source

Screening of Benzimidazole-Based Anthelmintics and Their Enantiomers as Repurposed Drug Candidates in Cancer Therapy

Pharmaceuticals, 2021
Repurposing of approved non-antitumor drugs represents a promising and affordable strategy that may help to increase the repertoire of effective anticancer drugs.
Rosalba Florio, S. Carradori, S. Veschi, D. Brocco, Teresa Di Genni, R. Cirilli, A. Casulli, A. Cama, L. De Lellis   +8 more
semanticscholar   +1 more source

The Antitumor Potentials of Benzimidazole Anthelmintics as Repurposing Drugs

Immune Network, 2020
The development of refractory tumor cells limits therapeutic efficacy in cancer by activating mechanisms that promote cellular proliferation, migration, invasion, metastasis, and survival.
D. Son, Eun-Sook Lee, S. Adunyah
semanticscholar   +1 more source

Modifcation of anthelmintic drugs by nanotechnology (review)

Российский паразитологический журнал, 2022
The purpose of the research is to analyze and summarize the literature data and the results of our own studies on the use of drug delivery systems and methods for increasing the solubility and efcacy of anthelmintic drugs.Helminthoses are one of the most
A. I. Varlamova, I. A. Arkhipov, S. S. Khalikov, M. V. Arisov   +3 more
doaj   +1 more source

Plant-Based Natural Products for the Discovery and Development of Novel Anthelmintics against Nematodes

Biomolecules, 2020
Intestinal parasitic nematodes infect approximately two billion people worldwide. In the absence of vaccines for human intestinal nematodes, control of infections currently relies mainly on chemotherapy, but resistance is an increasing problem.
Maoxuan Liu, Sujogya Kumar Panda, W. Luyten   +2 more
semanticscholar   +1 more source

A High-Throughput Phenotypic Screen of the ‘Pandemic Response Box’ Identifies a Quinoline Derivative with Significant Anthelmintic Activity

Pharmaceuticals, 2022
Parasitic nematodes cause diseases in livestock animals and major economic losses to the agricultural industry worldwide. Nematodes of the order Strongylida, including Haemonchus contortus, are particularly important.
Harrison T. Shanley, Aya C. Taki, Joseph J. Byrne, Abdul Jabbar, Tim N. C. Wells, Kirandeep Samby, Peter R. Boag, Nghi Nguyen, Brad E. Sleebs, Robin B. Gasser   +9 more
doaj   +1 more source