Results 101 to 110 of about 961,624 (248)

Umbilical cord blood natural killer cells for adoptive immunotherapy: identifying optimal starting material and processing parameters

Frontiers in Immunology
IntroductionUmbilical cord blood (UCB) is an attractive source of natural killer (NK) cells for the development of allogeneic ‘off-the-shelf’ cancer immunotherapies.
M. G. Kennedy, M. G. Kennedy, W. Patterson, S. T. Cox, S. T. Cox, L. Wynn, C. Stock da Cunha, C. Stock da Cunha, M. O’Dwyer, M. O’Dwyer, R. Danby, R. Danby, R. Danby, D. Hernandez, D. Hernandez   +14 more
doaj   +1 more source

Br. Anthony Krutch

Br.

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Data, not documents: Moving beyond theories of information‐seeking behavior to advance data discovery

Journal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 649-664, April 2025.
Abstract Many theories of human information behavior (HIB) assume that information objects are in text document format. This paper argues four important HIB theories are insufficient for describing users' search strategies for data because of assumptions about the attributes of objects that users seek.
Anthony J. Million, Jeremy York, Sara Lafia, Libby Hemphill   +3 more
wiley   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

Model‐informed optimal dose selection of golcadomide in combination with R‐CHOP in patients with previously untreated aggressive B‐cell lymphoma

British Journal of Clinical Pharmacology, EarlyView.
Aims Golcadomide is a potential first‐in‐class oral CELMoD™ agent for the treatment of lymphoma. This study aims to develop model‐informed drug development (MIDD) approaches to support optimal dose selection of golcadomide in combination with immunotherapy rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R‐CHOP) in alignment with ...
Xirong Zheng, Zhiling Yu, Mark Kaplan, Argyrios Gkasiamis, Akshay Sudhindra, Li Zhu, Manisha Lamba, Fan Wu   +7 more
wiley   +1 more source

Aircraft Level Thermal Management Analysis for Early Design Stages of Future Aircraft: Integration of Systems and Compartments into an Interacting Generic Approach

Engineering Proceedings
For future commercial aircraft having hybrid electric drivetrains, the impact of electrical power generation and distribution on heat production and required heat rejection is of a larger magnitude than for conventional aircraft.
Jaap van Muijden, Jos Aalbers
doaj   +1 more source

The theatre of Anthony Neilson

, 2018
Anthony Neilson is one of the most exciting and challenging voices in contemporary British theatre. This volume provides the first full-length study of his plays and his innovative rehearsal methodology.
Reid, Trish
core   +2 more sources

Paediatric clonidine medication errors: Findings from a multicentre French study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard, Anthony Facile, Marion Lepelley, Morgane Cellier, Laurent Chouchana, Sophie Gautier, Ramy Azzouz, Thierry Vial, Annie‐Pierre Jonville‐Bera   +8 more
wiley   +1 more source

A Registry‐Led Initiative Supporting United Kingdom Transplant Centers in Selection, Requesting, and Handling of Cord Blood Units for Hematopoietic Stem Cell Transplantation

Stem Cells Translational Medicine, 2019
Roger Horton, Laila Roberts, Rachael Cole, Daniel Gibson, Charlotte Green, Alexandra Ross, Nicole Stanley, Jessica Thew, Sharon Vivers, Irina Evseeva   +9 more
doaj   +1 more source

Re‐evaluating variability of circulating miR‐122 in healthy volunteers: Implications for biomarker qualification in drug‐induced liver injury

British Journal of Clinical Pharmacology, EarlyView.
Drug‐induced liver injury (DILI) remains a major challenge in clinical practice and drug development, and reliable biomarkers are still needed. MicroRNA‐122 (miR‐122) has shown promise, but reported inter‐individual variability in healthy populations has raised concerns about its clinical utility.
Irum Javid, Giusy Russomanno, Anthony Evans, Guruprasad P. Aithal, Shiva S. Forootan, Warren E. Glaab, Matthias Hackl, Joely Irlam, Kseniya Khamina‐Kotisch, Samantha Korver, Gerd A. Kullak‐Ublick, Sophia L. Samodelov, Christopher E. Goldring   +12 more
wiley   +1 more source