Natural Killer Cells in Asthma [PDF]
Frontiers in Immunology, 2013 The worldwide prevalence, morbidity, and mortality of asthma have dramatically increased over the last few decades and there is a clear need to identify new, effective, therapeutic and prophylactic strategies. Despite high numbers of NK cells in the lung
Khalil eKarimi, Paul eForsythe
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Uterine Natural Killer Cells [PDF]
Frontiers in Immunology, 2019 Natural killer (NK) cells are members of a rapidly expanding family of innate lymphoid cells (ILCs). While most previously studied NK cells were derived from the mouse spleen and circulate in the blood, recently others and we found tissue-resident NK ...
Dorothy K. Sojka +2 more
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Natural killer cells and natural killer T cells in Lyme arthritis [PDF]
Arthritis Research & Therapy, 2013 Introduction: Natural killer (NK) and natural killer T (NKT) cells provide a first line of defense against infection. However, these cells have not yet been examined in patients with Lyme arthritis, a late disease manifestation.
Drouin, Elise E +2 more
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Advances in augmenting infiltration of active natural killer cells into pediatric and adult solid tumors [PDF]
Molecular Therapy: OncologyAlthough adoptive natural killer cell therapies have been safe and somewhat effective in hematological malignancies, their performance in solid tumors is hindered by the solid tumor microenvironment, which impairs natural killer cell trafficking and ...
Shiori Eguchi +5 more
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Purification and antibody-free ex-vivo expansion of peripheral blood-derived autologous natural killer cells: A Malaysian case series on patient safety and tolerability [PDF]
SAGE Open Medical Case ReportsNatural killer cells are the most researched and employed cells for immunotherapy, which have expanded from autologous immune-enhanced therapies to genetically enhanced cell therapies such as chimeric antigen receptors natural killer cells.
Ramesh Thevendran +2 more
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Natural killer cell neoplasms [PDF]
Cancer, 2008 AbstractNatural killer (NK) cell tumors are an uncommon and heterogeneous group of disorders. The World Health Organization (WHO) classified mature NK cell neoplasms into 2 types: 1) extranodal NK cell lymphoma, nasal type and 2) aggressive NK cell leukemia. The mature NK cell tumors are prevalent in Asia and Central and South America.
Xiayuan, Liang, Douglas K, Graham
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Reduced proportion and activity of natural killer cells in patients with Graves’ disease
European Journal of Inflammation, 2020 Natural killer cells not only play important roles in protecting against viral infection and cancer but also involved in the pathogenesis of Graves’ disease.
Qingqing Yang +6 more
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Current landscape of clinical use of ex vivo expanded natural killer cells for cancer therapy [PDF]
Einstein (São Paulo)Natural Killer cells are immune leukocytes required for responses against tumor cells and virus-infected cells. In the last decade, natural killer cells have emerged as promising tools in cancer therapy, and clinical studies on patients treated with ...
Júlia Teixeira Cottas de Azevedo +11 more
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The activating receptors 2B4 and NTB-A, but not CRACC are subject to ligand-induced down-regulation on human natural killer cells [PDF]
, 2010 Activation of natural killer cells can be mediated by different receptors. Stimulation of the receptors 2B4, NTB-A and CRACC, members of the SLAM-related receptor family, induces cytotoxicity and cytokine production.
Carolin Böhm +4 more
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