Results 41 to 50 of about 8,634,563 (254)

Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic Hepatitis B virus infected patients [PDF]

, 2012
Natural killer (NK) cells play a critical role in innate antiviral immunity, but little is known about the impact of antiviral therapy on the frequency of NK cell subsets.
Xiumei Chi, Lv, J., Yu Pan, Zhigang Tian, Niu, J., Juan Lv, Weihua Xiao, Yan, H., Xu, D., Zhengkun Tu, Hu, X., Chi, X., Junqi Niu, Qinglong Jin, Xiao, W., Sun, H., Hou, J., Jinlin Hou, Hongqing Yan, Haibo Sun, Tian, Z., Tu, Z., Xiaoli Hu, Jin, Q., Pan, Y., Damo Xu   +25 more
core   +1 more source

Natural killer cells

Hematology/Oncology and Stem Cell Therapy, 2015
Natural killer (NK) cells constitute our bodies' frontline defense system, guarding against tumors and launching attacks against infections. The activities of NK cells are regulated by the interaction of various receptors expressed on their surfaces with cell surface ligands.
Mandal, Arundhati, Viswanathan, Chandra
openaire   +2 more sources

Stress-induced in vivo recruitment of human cytotoxic natural killer cells favors subsets with distinct receptor profiles and associates with increased epinephrine levels [PDF]

, 2015
Acute stress drives a 'high-alert' response in the immune system. Psychoactive drugs induce distinct stress hormone profiles, offering a sought-after opportunity to dissect the in vivo immunological effects of acute stress in humans.
Recher, Mike, Egli, Simon B., Marc B Bigler, Simon B Egli, Fabian S. Baldin (839693), Marc B. Bigler (839689), Florian A. Marquardsen (839694), Baldin, Fabian S., Schmied, Laurent, Cédric M Hysek, Christoph T. Berger, Laurent Schmied, Cédric M. Hysek (166535), Laurent Schmied (839692), Christoph T. Berger (189490), Gideon Hoenger (839691), Liechti, Matthias E., Simon B. Egli (839690), Christoph Hess, Fabian S Baldin, Matthias E Liechti, Marc B. Bigler, Cédric M. Hysek, Mike Recher, Hysek, Cédric M., Hess, Christoph, Berger, Christoph T., Christoph Hess (178783), Marquardsen, Florian A., Christoph T Berger, Hoenger, Gideon, Matthias E. Liechti (166584), Simon B. Egli, Gideon Hoenger, Fabian S. Baldin, Florian A Marquardsen, Mike Recher (36073), Matthias E. Liechti, Bigler, Marc B., Florian A. Marquardsen   +39 more
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Interferon therapy shifts natural killer subsets among Egyptian patients with chronic hepatitis C

Brazilian Journal of Infectious Diseases, 2010
Natural killer cells can be divided into five subpopulations based on the relative expression of CD16 and CD56 markers. The majority of natural killer cells are CD56dim, which are considered to be the main cytotoxic effectors.
Amal Fathy, Mohamed Mohy Eldin, Lobna Metwally, Mohamed Eida, Marwa Abdel-Rehim, Gamal Esmat   +5 more
doaj   +1 more source

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]

, 1998
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan, Matthias Ulbrecht, Ulbrecht, Matthias, Coligan, John E., Andrew G. Brooks, Brooks, AG, Borrego, F, Coligan, JE, Elisabeth H. Weiss, Brooks, Andrew G., Francisco Borrego, Borrego, Francisco, Weiss, Elisabeth H., Ulbrecht, M, Weiss, EH   +14 more
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Natural killer cells in hepatitis B virus infection

Brazilian Journal of Infectious Diseases, 2015
Natural killer cells are a unique type of lymphocytes with cytotoxic capacity, and play important roles against tumors and infections. Recently, natural killer cells have been increasingly valued in their effects in hepatitis B virus infection.
Shao-fei Wu, Wen-jing Wang, Yue-qiu Gao
doaj   +1 more source

Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells. [PDF]

, 2012
The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown.
Lohmeyer, Jürgen, Werner von Wulffen (141047), Gruber, Achim D., Gregor Bein (141053), Knoche, Angela, Kershaw, Olivia, Kranz, Sabine, Angela Knoche (141037), Holger Hackstein (141030), Hagel, Nicole, Angela Knoche, Wulffen, Werner von, Olivia Kershaw (141049), Holger Hackstein, Olivia Kershaw, Achim D. Gruber (141051), Nicole Hagel, Gregor Bein, Jürgen Lohmeyer, Sabine Kranz, Nicole Hagel (141033), Baal, Nelli, Bein, Gregor, Achim D Gruber, Jürgen Lohmeyer (141044), Nelli Baal (141055), Hackstein, Holger, Nelli Baal, Werner von Wulffen, Sabine Kranz (141040)   +29 more
core   +2 more sources

Killer instincts: natural killer cells as multifactorial cancer immunotherapy

Frontiers in Immunology, 2023
Natural killer (NK) cells integrate heterogeneous signals for activation and inhibition using germline-encoded receptors. These receptors are stochastically co-expressed, and their concurrent engagement and signaling can adjust the sensitivity of ...
Sarah Nersesian, Sarah Nersesian, Emily B. Carter, Emily B. Carter, Stacey N. Lee, Stacey N. Lee, Lauren P. Westhaver, Jeanette E. Boudreau, Jeanette E. Boudreau, Jeanette E. Boudreau   +9 more
doaj   +1 more source

Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]

, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews, Gotch, FM, Frances M. Gotch, Robey, Rebecca C, Bower, Mark, Rebecca C. Robey, Mark Bower, Matthews, Nick C, Goodier, Martin R, Bower, M, Goodier, MR, Robey, RC, Gotch, Frances M, Martin R. Goodier, Matthews, NC   +14 more
core   +1 more source

Advances in augmenting infiltration of active natural killer cells into pediatric and adult solid tumors

Molecular Therapy: Oncology
Although adoptive natural killer cell therapies have been safe and somewhat effective in hematological malignancies, their performance in solid tumors is hindered by the solid tumor microenvironment, which impairs natural killer cell trafficking and ...
Shiori Eguchi, Wen Luo, Hongwen Zhu, Jeremy M. Rosenblum, Anna R. Cooper, Mitchell S. Cairo   +5 more
doaj   +1 more source