Results 11 to 20 of about 401,106 (204)
Organ-specific features of natural killer cells. [PDF]
Nature Reviews Immunology, 2011 Natural killer (NK) cells can be swiftly mobilized by danger signals and are among the earliest arrivals at target organs of disease. However, the role of NK cells in mounting inflammatory responses is often complex and sometimes paradoxical.
La Cava, Antonio +3 more
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Targeting natural killer cells and natural killer T cells in cancer [PDF]
Nature Reviews Immunology, 2012 Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share some phenotypical and functional similarities. Both cell types can rapidly respond to the presence of tumour cells and participate in antitumour immune responses. This has prompted interest in the development of innovative cancer therapies that are based on
Vivier, Eric +4 more
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Current Biology, 1999 Perhaps, but probably not a long or healthy life. There is only one documented human case of an absolute NK cell deficiency, which was associated with recurrent life-threatening bacterial and viral infections.
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Natural Killer Cell Memory [PDF]
Immunity, 2015 Natural killer (NK) cells have historically been considered short-lived cytolytic cells that can rapidly respond against pathogens and tumors in an antigen-independent manner and then undergo cell death. Recently, however, NK cells have been shown to possess traits of adaptive immunity and can acquire immunological memory in a manner similar to that of
O’Sullivan, Timothy E +2 more
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Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells. [PDF]
, 2012 The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown.
Baal, Nelli +9 more
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BMC Immunology, 2019 Background Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors.
Alexandra Tremblay-McLean +4 more
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Natural killer cell in the development and treatment of head and neck squamous cell carcinoma [PDF]
Yixue xinzhi zazhi, 2021 Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors in the world. It has a high metastasis rate and a poor prognosis.
Lu-Ming WANG, Shang XIE
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SnapShot: Natural Killer Cells
Cell, 2020 NK cells are broadly distributed innate lymphoid cells (ILCs) encompassing distinct populations based on CD11b and CD27 expression in mice or CD56 intensity in humans. Involved in anti-viral and anti-tumor immunity thanks to their cytokines and chemokines secretion as well as their cytotoxic capabilities, NK cells have emerged as a promising ...
Crinier, Adeline +3 more
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In vivo generation of decidual natural killer cells from resident hematopoietic progenitors
Haematologica, 2014 Decidual natural killer cells accumulate at the fetal-maternal interface and play a key role in a successful pregnancy. However, their origin is still unknown.
Laura Chiossone +9 more
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Evasion of NK cell immune surveillance via the vimentin-mediated cytoskeleton remodeling
Frontiers in Immunology, 2022 Cancer immunotherapy uses the immune system to achieve therapeutic effects; however, its effect is still limited. Therefore, in addition to immune checkpoint-based treatment, the development of other strategies that can inhibit cancer cells from ...
Jei-Ming Peng +8 more
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