Results 11 to 20 of about 18,274 (245)

Kanglexin protects against cardiac fibrosis and dysfunction in mice by TGF-β1/ERK1/2 noncanonical pathway

open access: yesFrontiers in Pharmacology, 2021
Cardiac fibrosis is a common pathological manifestation accompanied by various heart diseases, and antifibrotic therapy is an effective strategy to prevent diverse pathological processes of the cardiovascular system.
Xue Liu   +18 more
doaj   +1 more source

XLII.—Researches on the anthraquinones [PDF]

open access: yesJ. Chem. Soc., Trans., 1908
n ...
Bentley, William Henry   +1 more
openaire   +2 more sources

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system [PDF]

open access: yesApplied and Environmental Microbiology, 1982
The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraquinone derivatives tested were mutagenic for TA1537 exclusively. None of
D F, Liberman   +4 more
openaire   +2 more sources

Natural Anthraquinones as Potential Akt1-Targeted Anticancer Agents [PDF]

open access: yesAvicenna Journal of Medical Biochemistry
Background: The phosphoinositide 3-kinase/protein kinase B (Akt)/mammalian target of the rapamycin signaling pathway is crucial in cancer progression. Akt1, a vital pathway component, has emerged as a promising therapeutic target.
Shokoofeh Jamshidi   +3 more
doaj   +1 more source

In Vitro Anticancer Screening and Preliminary Mechanistic Study of A-Ring Substituted Anthraquinone Derivatives

open access: yesCells, 2022
Anthraquinone derivatives exhibit various biological activities, e.g., antifungal, antibacterial and in vitro antiviral activities. They are naturally produced in many fungal and plant families such as Rhamnaceae or Fabaceae. Furthermore, they were found
Ibrahim Morgan   +2 more
doaj   +1 more source

Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities

open access: yesMarine Drugs, 2016
Anthraquinones and their derivatives constitute a large group of quinoid compounds with about 700 molecules described. They are widespread in fungi and their chemical diversity and biological activities recently attracted attention of industries in such ...
Mireille Fouillaud   +4 more
doaj   +1 more source

New Anthraquinone Derivatives from

open access: yesNatural Product Communications, 2013
A phytochemical study of Geosmithia lavendula Pitt led to the isolation of three new anthraquinones: 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone (1), 2-acetyl-1,4,5,7-tetrahydroxy-9,10-anthraquinone (2), and 1-acetyl-2,4,5,6,7-pentahydroxy-9,10 ...
Lourin G. Malak   +5 more
doaj   +1 more source

An Example of a Novel Efficient Plant Extraction Technique: Electromagnetic Induction Heating

open access: yesMolecules, 2018
A simple and easy to handle extraction procedure based on the use of electromagnetic induction heating is described. To assess the potential, scopes, and limitations of this novel process, extraction and subsequent HPLC quantification of emodin from an ...
Francesco Epifano   +4 more
doaj   +1 more source

Hepatotoxic components and attenuation of polygonimultiflori radix praeparata induced idiosyncratic liver injury

open access: yes生物医学转化, 2021
Objective Polygoni Multiflori Radix (PM, He-Shou-Wu), is used as a reputable tonifying traditional Chinese medicine for a long time. However, in recent years, the liver injury caused by PM or its preparations attracted wide attention.
Ren Hongwei   +9 more
doaj   +1 more source

The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes

open access: yesMolecules, 2021
Human glutathione transferase A1-1 (hGSTA1-1) contributes to developing resistance to anticancer drugs and, therefore, is promising in terms of drug-design targets for coping with this phenomenon.
Mohammed Hamed Alqarni   +3 more
doaj   +1 more source

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