Anthrax has been feared for its high mortality in animals and humans for centuries. The etiologic agent is considered a potentially devastating bioweapon, and since 1876―when Robert Koch demonstrated that Bacillus anthracis caused anthrax―it has been ...
William A. Bower +6 more
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A single-dose PLGA encapsulated protective antigen domain 4 nanoformulation protects mice against Bacillus anthracis spore challenge. [PDF]
Bacillus anthracis, the etiological agent of anthrax, is a major bioterror agent. Vaccination is the most effective prophylactic measure available against anthrax. Currently available anthrax vaccines have issues of the multiple booster dose requirement,
Manish Manish +4 more
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Persistent anthrax as a major driver of wildlife mortality in a tropical rainforest [PDF]
Anthrax is a globally important animal disease and zoonosis. Despite this, our current knowledge of anthrax ecology is largely limited to arid ecosystems, where outbreaks are most commonly reported.
A McKenna +104 more
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Features of anthrax natural foci and Bacillus anthracis ecology
Anthrax remains a global problem, both for veterinary and human medicine, due to the wide spread of its soil foci throughout the world. The ability to sporulate is the main feature of Bacillus anthracis, which allows the pathogen to persist in the ...
A. P. Rodionov +4 more
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Erythrocytic mobilization enhanced by the granulocyte colony-stimulating factor is associated with reduced anthrax-lethal-toxin-induced mortality in mice. [PDF]
Anthrax lethal toxin (LT), one of the primary virulence factors of Bacillus anthracis, causes anthrax-like symptoms and death in animals. Experiments have indicated that levels of erythrocytopenia and hypoxic stress are associated with disease severity ...
Hsin-Hou Chang +9 more
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Epidemiological and Epizootiological Situation on Anthrax in 2014, and Prognosis for 2015
Presented are the results of analysis of epidemiological and epizootiological situation on anthrax across the Russian Federation and around the world in 2014. Anthrax morbidity rates in Russia have increased as compared to the previous year, but have not
A. G. Ryazanova +7 more
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THE CURRENT SITUATION ON ANTHRAX IN RUSSIA AND IN THE WORLD. MAIN TRENDS AND FEATURES
The current situation on anthrax is characterized as unstable. Instability is associated with recurring epizootic outbreaks complicated by human anthrax cases, as people contract infection mainly through contact with sick animals, their carcasses or ...
E. I. Eremenko +2 more
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Heme catabolism in the causative agent of anthrax
SummaryA challenge common to all bacterial pathogens is to acquire nutrients from hostile host environments. Iron is an important cofactor required for essential cellular processes such as DNA repair, energy production and redox balance. Within a mammalian host, most iron is sequestered within heme, which in turn is predominantly bound by hemoglobin ...
Justin Clark +5 more
openaire +3 more sources
Distribution of hairpin-loop structures in plasmids of anthrax infectious agent [PDF]
An important biological function of hairpin-loop structures is the defense of RNA transcripts from degradation by different factors as well as the transcription regulation due to their formation in transcription terminators. The patterns of thermodynamically stable perfect and imperfect inverted repeats were determined for pXO1 and pXO2 plasmids of ...
O. Yu. Limanskaya, A. P. Limanskii
openaire +1 more source
Bacillus anthracis, the causative agent of anthrax in humans, livestock, and wildlife, exists in a community with hundreds of other species of bacteria in the environment. Work on the genetics of these communities has shown that B.
Hsiao-Hsuan Wang +3 more
doaj +1 more source

