Results 101 to 110 of about 1,237,816 (284)

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini   +2 more
wiley   +1 more source

Autonomous Nanomedicine: Closing the Biological Validation Gap

open access: yesExploration, EarlyView.
Delivery of nanoparticles to tumors has not improved in over fifteen years, and biological testing remains slow and separate from formulation design. This review proposes adding a Biology step to the design cycle, using organ chips and patient‐derived organoids, and assesses the readiness of each required technology.
Yan Jun Lin, Izabella Komperda
wiley   +1 more source

ALONE IN THE UNIVERSE

open access: yesZygon, 2016
We are probably alone in the universe—a conclusion based on observations of over 4,000 exoplanets and fundamental physical constraints. This article updates earlier arguments with the latest astrophysical results.
doaj   +2 more sources

Assemblages of care: Moral economies, classed labor, and affective exhaustion among Karachi's working middle‐class women

open access: yesFeminist Anthropology, EarlyView.
Abstract This article explores how working middle‐class women in Karachi navigate the intersecting burdens of care and self‐care within the affective, infrastructural, and ideological conditions of urban precarity. Drawing on twelve semi‐structured interviews conducted across homes, workplaces, and cafés in the city, seven of which anchor the primary ...
Muhammad Huzaifa
wiley   +1 more source

Anthropic principle as a consequence of the time emergence [PDF]

open access: yes
The paper considers the philosophical component of the approach to the time as an emergent phenomenon absent at the fundamental level. The anthropic principle is shown as arising from the time emergence. Consciousness is shown as an epiphenomenon in such
Smirnov, Andrey
core   +3 more sources

History and Creativity in Fr. George Florovsky's Theology

open access: yesForum Theologicum Sardicense
Roussina Torosyan, History and Creativity in Fr. George Florovs-ky's Theology. The article aims to present the theological understanding of Fr. Florovsky on history and time.
Roussina Torosyan
doaj  

Antropoconstructs of self-conscious and activity [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011
It is examined trends in the conceptualization of educational development. It is shown that the culture of bodily health should be subject to planning and mental control.
Dmitriev Stanislav Vladimirovich
doaj  

Therapeutic orphans no more: Revisiting the ethical justification for excluding pregnant women from pharmaceutical clinical trials

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract For six decades, pregnant women have been routinely excluded from pharmaceutical clinical trials, a practice rooted in a protectionist ethic that emerged after the thalidomide tragedy. This narrative review examines whether that exclusion remains ethically justifiable, drawing on the obstetric, pharmacological, and bioethical literature ...
Camila Kruger Cabar   +1 more
wiley   +1 more source

Benchmarking gut microbiome indices within and across populations

open access: yesiMetaOmics, EarlyView.
We compared 10 widely used gut microbiome indices in 12,561 American Gut Project participants and 10 external cohorts, testing how well each distinguished people with healthy lifestyles, responded to 79 environmental factors, and associated with 14 chronic conditions. No single index performed best on all three tasks.
Yu Sun   +6 more
wiley   +1 more source

Una narración no es una ecuación: principios metafísicos de la cosmología estándar

open access: yesMemoria y Civilización, 2006
This paper explains that the so-called "Standard Cosmology", a means of chronicling the universe from the Big Bang until the present, is a mixture on three levels: experimental results, scientific hypotheses and the traditional narrative construction ...
José Carlos Bermejo Barrera
doaj  

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