Results 221 to 230 of about 70,873 (256)
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Chapter 1. Antipsychotic and Anti-anxiety Agents
1969Publisher Summary This chapter discusses results of studies focusing on antipsychotic and antianxiety agents. Studies revealed that medazepam alleviates anxiety and tension in children and adults with minimal sedative side effect and without impairment of working capacity or normal alertness.
Irwin J. Pachter, Alan A. Rubin
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Chapter I. Antipsychotic and Anti-anxiety Agents
1968Publisher Summary This chapter elaborates on antipsychotic and antianxiety agents. The reported contribution of pyrrole nuclei to the sedative action of ketone derivatives encouraged the synthesis of relatives of ketone derivatives in which the benzene ring was replaced by pyrrole.
Irwin J. Pachter, Alan A. Rubin
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Ondansetron: A Novel Anti-anxiety Agent
1991Although the widely used benzodiazepines for control of anxiety have met with high patient acceptance, there is a hesitation about long-term use owing to the possibility of dependence. The new azaspirodecanedione compounds such as buspirone (Buspar) are free from dependence but raise the spectre of tardive dyskinesia since they are derivatives of the ...
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Chapter 3 Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
1979Publisher Summary This chapter summarizes the nature of the benzodiazepine receptor that has been characterized further, by the demonstration that a single class of binding sites exists in rat brain for a structurally diverse series of benzodiazepines.
Joel G. Berger, Louis C. Iorio
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Chapter 1. Anti-Anxiety Agents and Sedative-Hypnotics
1985Publisher Summary In this chapter, the pharmacological actions of different anti-anxiety agents and sedative-aypnotics have been discussed with current references. Current evidence indicates that most anxiolytic and sedative-hypnotic drugs exert their pharmacological actions by binding to discrete neuronal recognition sites, consisting of ...
Barbara Petrack, Naokata Yokoyama
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Behavioural Validation of a Light/Dark Choice Procedure for Testing Anti-Anxiety Agents
Behavioural Processes, 1989In order to teat the behavioural value of a two-chambered light/dark choice procedure used for pharmacological studies, we investigated the effects of several internal and external factors on two variables: the time spent by mice in the lit box (TLB) and the number of transitions between the lit box and the dark one.
R, Misslin, C, Belzung, E, Vogel
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Chapter 1. Antipsychotic and Anti-anxiety Agents
1970Publisher Summary This chapter discusses the results of studies focusing on antipsychotic and anti-anxiety agents. A double blind controlled study showed an approximately 10% better response in schizophrenic patients with droperidol than with haloperidol.
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Chapter 32 Hypnotics and anti-anxiety agents
1997Summary Depression of the central nervous system can be achieved with a wide variety of chemical agents. Depending on dose, increasing levels of effect consisting of (a) anti-anxiety effects, (b) sedation, (c) sleep, (d) anesthesia, and (e) coma (with risk of a fatal outcome) may be produced. Frequently the same agent may be used at a greater dose to
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Chapter 3. Anti-Anxiety Agents, Anticonvulsants and Sedative-Hypnotics
1978Publisher Summary A specific benzodiazepine receptor has been found in rat and human brain cells that might mediate their pharmacological activities. Binding sites in the rat are unevenly distributed throughout the brain, and a loose parallel between the pharmacological potency and receptor affinity is found.
William J. Houlihan, Gregory B. Bennett
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Chapter 4. Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
1981Publisher Summary Rapid advances have been made in understanding the neurochemical mechanisms of benzodiazepines (BZs) and similar compounds responsible for their therapeutic actions. The “GABA hypothesis” relating to the actions of BZs in the brain continues to gain support.
Richard C. Effland, Manfred F. Försch
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